Khater Nazih, Khauli Raja, Shahait Mohammad, Degheili Jad, Khalifeh Ibrahim, Aoun Jessica
American University of Beirut, Division of Urology and Kidney Transplantation, Beirut, Lebanon.
Urol Int. 2013;91(4):373-83. doi: 10.1159/000354394. Epub 2013 Aug 29.
Renal solitary fibrous tumors (SFTs) are spindle cell neoplasms of mesenchymal origin, and very rare with only 46 cases reported worldwide to date. It is crucial to differentiate this tumor from other tumors of the kidney, so as to avoid unnecessary treatment. Therefore, our objective was to review reports of renal SFTs, their clinical presentations, imaging methods, and surgical management, updated to 2013.
We retrospectively reviewed articles published in the USA, Europe, and Asia from 1996 to date using PubMed, Medscape, Medline, and several major journals. We report on areas of controversy and well-established guidelines.
We reviewed 58 articles which confirmed, with a high level of evidence-based medicine, that the male-to-female ratio is equal and their most common presentation is an incidental finding on a radiological study, in which it is difficult to differentiate them from renal cell carcinoma. Nephrectomy is the gold standard treatment, with almost no recurrence.
In symptomatic patients, complete surgical resection of renal SFTs may provide a very good outcome, with almost no recurrence.
肾孤立性纤维瘤(SFTs)是间叶组织起源的梭形细胞瘤,非常罕见,迄今为止全球仅报道46例。将此肿瘤与其他肾脏肿瘤区分开来至关重要,以避免不必要的治疗。因此,我们的目的是回顾截至2013年肾SFTs的报告、其临床表现、影像学方法及手术治疗。
我们使用PubMed、Medscape、Medline及几本主要期刊,回顾了1996年至今在美国、欧洲和亚洲发表的文章。我们报告了存在争议的领域及公认的指南。
我们回顾了58篇文章,这些文章以高水平循证医学证实,男女比例相等,其最常见表现是在影像学检查中偶然发现,在此检查中难以将它们与肾细胞癌区分开来。肾切除术是金标准治疗方法,几乎无复发。
对于有症状的患者,完整手术切除肾SFTs可能会带来非常好的结果,几乎无复发。