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博茨瓦纳的宫颈癌:筛查与治疗项目的现状及未来举措

Cervical Cancer in Botswana: Current State and Future Steps for Screening and Treatment Programs.

作者信息

Grover Surbhi, Raesima Mmakgomo, Bvochora-Nsingo Memory, Chiyapo Sebathu P, Balang Dawn, Tapela Neo, Balogun Onyinye, Kayembe Mukendi K A, Russell Anthony H, Monare Barati, Tanyala Senate, Bhat Jailakshmi, Thipe Kealeboga, Nchunga Metlha, Mayisela Susan, Kizito Balladiah, Ho-Foster Ari, Gaolebale Babe Eunice, Gaolebale Ponatshego A, Efstathiou Jason A, Dryden-Peterson Scott, Zetola Nicola, Hahn Stephen M, Robertson Erle S, Lin Lilie L, Morroni Chelsea, Ramogola-Masire Doreen

机构信息

Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA , USA ; Botswana University of Pennsylvania Partnership , Gaborone , Botswana.

National Cervical Cancer Prevention Programme, Ministry of Health , Gaborone , Botswana.

出版信息

Front Oncol. 2015 Nov 3;5:239. doi: 10.3389/fonc.2015.00239. eCollection 2015.

Abstract

Botswana has a high burden of cervical cancer due to a limited screening program and high HIV prevalence. About 60% of the cervical cancer patients are HIV positive; most present with advanced cervical disease. Through initiatives by the Botswana Ministry of Health and various strategic partnerships, strides have been made in treatment of pre-invasive and invasive cancer. The See and Treat program for cervical cancer is expanding throughout the country. Starting in 2015, school-going girls will be vaccinated against HPV. In regards to treatment of invasive cancer, a multidisciplinary clinic has been initiated at the main oncology hospital to streamline care. However, challenges remain such as delays in treatment, lack of trained human personnel, limited follow-up care, and little patient education. Despite improvements in the care of pre-invasive and invasive cervical cancer patients, for declines in cervical cancer-related morbidity and mortality to be achieved, Botswana needs to continue to invest in decreasing the burden of disease and improving patient outcomes of patients with cervical cancer.

摘要

由于筛查项目有限且艾滋病毒感染率高,博茨瓦纳宫颈癌负担沉重。约60%的宫颈癌患者艾滋病毒呈阳性;大多数患者表现为晚期宫颈疾病。通过博茨瓦纳卫生部的举措及各种战略伙伴关系,在治疗癌前病变和浸润性癌症方面已取得进展。宫颈癌的“筛查与治疗”项目正在全国范围内扩大。从2015年开始,在校女生将接种人乳头瘤病毒疫苗。在浸润性癌症治疗方面,主要肿瘤医院已开设多学科诊所,以简化护理流程。然而,挑战依然存在,如治疗延误、缺乏训练有素的人员、后续护理有限以及患者教育不足。尽管癌前病变和浸润性宫颈癌患者的护理有所改善,但要实现宫颈癌相关发病率和死亡率的下降,博茨瓦纳需要继续投入,以减轻疾病负担并改善宫颈癌患者的治疗效果。

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