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[西班牙加泰罗尼亚近期麻疹和风疹疫情监测计划]

[Surveillance Plan on Recent Outbreak of Measles and Rubella in Catalonia, Spain].

作者信息

Jané Mireia, Torner Nuria, Vidal Ma José

出版信息

Rev Esp Salud Publica. 2015 Jul-Aug;89(4):397-406. doi: 10.4321/S1135-57272015000400008.

DOI:10.4321/S1135-57272015000400008
PMID:26580795
Abstract

Measles and rubella are two immuno-preventive illnesses. In Catalonia, since 1988 all children are given two doses of measles and rubella vaccine with high levels of vaccination coverage. The measles elimination programme has been carried out since 1990 in Catalonia. This programme includes achieving and keeping high immunization levels among population with high vaccination coverage, intense epidemiological surveillance and an immediate response to the appearance of a case or outbreak. In 2014, the measles incidence rate was 1.9 cases/ 100,000 inhabitants. There were 4 recent outbreaks in 2006, 2011, 2013 and 2014 that affected 381, 289, 31 and 124 people respectively. All outbreaks were triggered by an imported case. In 2011 and 2014 measles outbreaks, 6% and 5.5% of affected people were health care workers. All outbreaks presented a great variety of measles genotypes. Concerning rubella elimination programme, since 2002, 68 cases of postnatal rubella and 5 cases of congenital rubella were confirmed. Regarding measles and rubella surveillance and control, in addition to strengthen vaccination coverage, it is essential immediate notification, within the first 24 hours since suspicion and laboratory confirmation. In addition there is a need to enforce vaccination among health care workers as well as in other susceptible and unvaccinated people. It is recommended to vaccinate all people who were born after 1966 and who have not been vaccinated with two doses of trivalent measles-mumps-rubella vaccine. Furthermore, we have to emphasize that the progress concerning genotypes study allows identifying various imported cases from other European countries with active outbreaks, aspect that makes easier the surveillance of these illnesses.

摘要

麻疹和风疹是两种可通过免疫预防的疾病。在加泰罗尼亚,自1988年以来,所有儿童均接种两剂麻疹风疹疫苗,疫苗接种覆盖率很高。自1990年起,加泰罗尼亚实施了麻疹消除计划。该计划包括在疫苗接种覆盖率高的人群中实现并维持高免疫水平、强化流行病学监测以及对病例或疫情的出现立即做出反应。2014年,麻疹发病率为每10万居民1.9例。近期在2006年、2011年、2013年和2014年发生了4次疫情,分别影响了381人、289人、31人和124人。所有疫情均由输入病例引发。在2011年和2014年的麻疹疫情中,6%和5.5%的感染者为医护人员。所有疫情呈现出多种麻疹基因型。关于风疹消除计划,自2002年以来,确诊了68例产后风疹病例和5例先天性风疹病例。关于麻疹和风疹的监测与控制,除了提高疫苗接种覆盖率外,在怀疑并实验室确认后的24小时内立即通报至关重要。此外,有必要对医护人员以及其他易感和未接种疫苗的人群强制接种疫苗。建议对1966年以后出生且未接种两剂三价麻疹-腮腺炎-风疹疫苗的所有人进行接种。此外,我们必须强调,基因型研究方面的进展有助于识别来自其他欧洲国家有活跃疫情的各种输入病例,这使得对这些疾病的监测更加容易。

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