Hochedez Patrick, Theodose Rafaelle, Olive Claude, Bourhy Pascale, Hurtrel Guillaume, Vignier Nicolas, Mehdaoui Hossein, Valentino Ruddy, Martinez Roland, Delord Jean-Marie, Herrmann Cécile, Lamaury Isabelle, Césaire Raymond, Picardeau Mathieu, Cabié André
Emerg Infect Dis. 2015 Dec;21(12):2221-4. doi: 10.3201/eid2112.141099.
To identify factors associated with disease severity, we examined 102 patients with quantitative PCR-confirmed leptospirosis in Martinique during 2010-2013. Associated factors were hypotension, chest auscultation abnormalities, icterus, oligo/anuria, thrombocytopenia, prothrombin time <68%, high levels of leptospiremia, and infection with L. interrogans serovar Icterohaemorrhagiae/Copenhageni.
为了确定与疾病严重程度相关的因素，我们对2010年至2013年期间在马提尼克岛102例经定量PCR确诊的钩端螺旋体病患者进行了检查。相关因素包括低血压、胸部听诊异常、黄疸、少尿/无尿、血小板减少、凝血酶原时间<68%、钩端螺旋体血症水平高以及感染问号钩端螺旋体黄疸出血型/哥本哈根型。
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