Avrutskiĭ G Ia, Neduva A A, Sulukhiia S V, Iakovlev A V
Zh Nevropatol Psikhiatr Im S S Korsakova. 1989;89(2):131-5.
In 123 patients the peculiarities of formation and effectiveness of insulin coma (IC) were studied under drug therapy as compared with 49 drug-free patients. Pharmacotherapy preceding the ICs produced uneven effect on its course. Artefact course of IC was most frequently observed after mageptil, chlorpromazine melipramine treatment, and to a lesser extent--after haloperidol, triphtazin, amitriptyline. It was virtually absent after benzodiazepines. The autonomic manifestations in IC and the harmony if its development and clinical picture, markedly changing under drug treatment, were exposed as predictors of the efficiency of IC therapy.
对123例接受药物治疗的患者与49例未接受药物治疗的患者进行了胰岛素昏迷（IC）形成特点及有效性的研究。IC治疗前的药物治疗对其病程产生了不均衡的影响。在使用美加明、氯丙嗪、丙咪嗪治疗后，最常观察到IC的假象病程，在使用氟哌啶醇、曲拉唑嗪、阿米替林治疗后观察到的程度较轻。在使用苯二氮䓬类药物后几乎未观察到。IC中的自主神经表现及其发展与临床表现的协调性在药物治疗下显著改变，被视为IC治疗效果的预测指标。
