Kalinin V V, Rudik V A
Zh Nevropatol Psikhiatr Im S S Korsakova. 1986;86(5):745-9.
The efficacy of intensive insulin coma therapy (IICT) and individually adjusted psychopharmacotherapy (IAT) was studied in schizophrenics in a month after the treatment initiation. Comparison of the efficacy of these 2 methods showed that the insulin treatment led to a sharper differentiation between patients with favourable and unfavourable therapeutic effect. The duration of schizophrenia did not affect the results of IICT. This method was more effective in schizoaffective syndromes in the framework of periodic schizophrenia, as well as in paroxysmal schizophrenia when it closely resembled the former. IICT was poorly effective in neurosis-like and hallucination-paranoid syndromes in the framework of the continuous course of schizophrenia. The rate of disappearance of psychotic symptomatology in the insulin therapy correlated with the degree of the course therapeutic effect.
在治疗开始后的一个月内，对精神分裂症患者进行了强化胰岛素昏迷疗法（IICT）和个体化调整精神药物疗法（IAT）疗效的研究。这两种方法疗效的比较表明，胰岛素治疗使治疗效果良好和不佳的患者之间差异更为明显。精神分裂症的病程长短并不影响强化胰岛素昏迷疗法的效果。在周期性精神分裂症框架下的分裂情感综合征中，以及在与前者极为相似的阵发性精神分裂症中，该方法更为有效。在持续性精神分裂症框架下的神经症样和幻觉偏执综合征中，强化胰岛素昏迷疗法效果不佳。胰岛素治疗中精神病症状消失的速度与病程治疗效果的程度相关。
