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中国社区老年女性生殖变量与代谢综合征之间的关联

Association between reproductive variables and metabolic syndrome in chinese community elderly women.

作者信息

Liu Miao, He Yao, Jiang Bin, Wu Lei, Wang Jianhua, Yang Shanshan, Wang Yiyan, Li Xiaoying

机构信息

Institute of Geriatrics, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China; Beijing Key Laboratory of Aging and Geriatrics, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.

Institute of Geriatrics, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China; Beijing Key Laboratory of Aging and Geriatrics, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China; State Key Laboratory of Kidney Disease, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.

出版信息

Arch Gerontol Geriatr. 2016 Mar-Apr;63:78-84. doi: 10.1016/j.archger.2015.11.003. Epub 2015 Nov 10.

Abstract

OBJECTIVE

This study aimed to evaluate the association between reproductive variables and metabolic syndrome (MetS) among Chinese community elderly women.

METHODS

We conducted a cross-sectional study in a Beijing urban district. A two-stage stratified clustering sampling method was used and 1251 elderly women were included.

RESULTS

The prevalence of MetS was 65.1% in this population. Women with MetS had younger menarche age, a greater number of years after menopause, higher gravidity and parity. The prevalence of MetS showed an increasing trend for tertiles of years after menopause (p=0.002) and number of children (p<0.001), while decreasing trend for menarche age (p=0.021). Logistic regression showed ORs of age at menarche, years after menopause and number of children for MetS were 0.94, 1.40, and 1.36 for second and 0.63, 1.58, and 1.75 for last tertiles.

CONCLUSION

There is strong association between reproductive variables and higher risk of MetS. Simple information on timing of menarche and menopause could help identify women who may have higher risk of getting MetS and take early action to prevent related chronic diseases.

摘要

目的

本研究旨在评估中国社区老年女性生殖变量与代谢综合征(MetS)之间的关联。

方法

我们在北京一个城区进行了一项横断面研究。采用两阶段分层整群抽样方法,纳入了1251名老年女性。

结果

该人群中MetS的患病率为65.1%。患有MetS的女性月经初潮年龄更小,绝经后年限更长,妊娠次数和产次更多。MetS的患病率在绝经后年限的三分位数(p = 0.002)和子女数量(p < 0.001)方面呈上升趋势,而在月经初潮年龄方面呈下降趋势(p = 0.021)。逻辑回归显示,月经初潮年龄处于第二和最后三分位数时,其MetS的比值比分别为0.94、1.40和1.36,绝经后年限的比值比分别为0.63、1.58和1.75,子女数量的比值比分别为1.36和1.75。

结论

生殖变量与MetS的高风险之间存在密切关联。关于月经初潮和绝经时间的简单信息有助于识别可能患MetS风险较高的女性,并采取早期行动预防相关慢性疾病。

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