一份引发心律失常灾难的抗生素配方。

An antibiotic recipe for an arrhythmic disaster.

作者信息

McCutcheon Keir, Manga Pravin

机构信息

Division of Cardiology, Department of Medicine, University of the Witwatersrand, and Charlotte Maxeke Academic Hospital, Johannesburg, South Africa.

出版信息

Cardiovasc J Afr. 2015 May-Jun;26(3):143-5. doi: 10.5830/CVJA-2015-006.

DOI:10.5830/CVJA-2015-006

PMID:26592910

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4763463/

Abstract

We describe the case of a patient who developed torsade de pointes during temporary pacemaker insertion after administration of intravenous erythromycin. The case highlights the dangers of administering drugs that prolong the QT interval in patients with complete atrioventricular block, and we discuss the underlying pathophysiological recipe that can lead to a potential arrhythmic disaster.

摘要

我们描述了一例患者，该患者在静脉注射红霉素后进行临时起搏器植入时发生了尖端扭转型室速。该病例凸显了在完全性房室传导阻滞患者中使用延长QT间期药物的危险性，并且我们讨论了可能导致潜在心律失常灾难的潜在病理生理机制。