Drent Marjolein, Strookappe Bert, Hoitsma Elske, De Vries Jolanda
Department of Pharmacology and Toxicology, Faculty of Health, Medicine and Life Science, Maastricht University, PO Box 616, Maastricht 6200 MD, The Netherlands; ILD Center of Excellence, St. Antonius Hospital, Koekoekslaan 1, Nieuwegein 3435 CM, The Netherlands; ILD Care Foundation Research Team, PO Box 18, Bennekom 6720 AA, The Netherlands.
ILD Care Foundation Research Team, PO Box 18, Bennekom 6720 AA, The Netherlands; Department of Physical Therapy, Gelderse Vallei Hospital (ZGV), PO Box 9025, Ede 6710HN, The Netherlands.
Clin Chest Med. 2015 Dec;36(4):727-37. doi: 10.1016/j.ccm.2015.08.013. Epub 2015 Sep 26.
Sarcoidosis is a multisystem disorder of unknown cause(s). Less specific disabling symptoms, including fatigue and physical impairments, may have a major influence on the daily activities and the social and professional lives of the patients, resulting in a reduced quality of life. A multidisciplinary approach focusing on somatic and psychosocial aspects is recommended. Patients self-perceived knowledge about the importance of exercise and lifestyle should be improved. Developing the most appropriate therapeutic approach for sarcoidosis requires careful consideration of the possible impact of fatigue, small fiber neuropathy related symptoms, pain, cognitive functioning, and coping strategies. Personalized medicine and appropriate communication are beneficial.
结节病是一种病因不明的多系统疾病。包括疲劳和身体损伤在内的不太特异的致残症状可能对患者的日常活动以及社交和职业生活产生重大影响，从而导致生活质量下降。建议采用注重躯体和心理社会方面的多学科方法。应提高患者对运动和生活方式重要性的自我认知。制定最适合结节病的治疗方法需要仔细考虑疲劳、小纤维神经病变相关症状、疼痛、认知功能和应对策略可能产生的影响。个性化医疗和适当的沟通是有益的。
