Tikhonovich M V, Iojleva E Je, Gavrilova S A
Klin Med (Mosk). 2015;93(7):14-20.
This paper focuses on the risk factors of primay and secondary proliferative vitreoretinopathy, modern views of pathophysiology of this disease, and the role of inflammation in its development. Special attention is given to the involvement of pigment epithelial cells, macrophages, hyalocytes, gliocytes, supporting fibers (Muller's cells), mediators of inflammation, such as cytokines, chemokines, and growth factors, with reference to their interaction in the processes of proliferation and development of retinal membranes.
本文重点关注原发性和继发性增殖性玻璃体视网膜病变的危险因素、该疾病病理生理学的现代观点以及炎症在其发展中的作用。特别关注色素上皮细胞、巨噬细胞、玻璃体细胞、神经胶质细胞、支持纤维(米勒细胞)、炎症介质(如细胞因子、趋化因子和生长因子)的参与情况,并参考它们在视网膜膜增殖和发育过程中的相互作用。