Ahangari Zohreh, Nasser Mona, Mahdian Mina, Fedorowicz Zbys, Marchesan Melissa A
Department of Endodontics and Iranian Dental Research Centre, Shahid Beheshti School of Dentistry, Daneshjou Boulevard, Evin, Tehran, Iran, 19834.
Cochrane Database Syst Rev. 2015 Nov 24;2015(11):CD008003. doi: 10.1002/14651858.CD008003.pub3.
External root resorption is a pathological process, which tends to occur following a wide range of mechanical or chemical stimuli such as infection, pressure, trauma or orthodontic tooth movement. Although it is predominantly detected by radiography, in some cases root resorption may be identified by clinical symptoms such as pain, swelling and mobility of the tooth. Treatment alternatives are case-dependent and aim to address the cause of the resorption and aid the regeneration of the resorptive lesion.
To evaluate the effectiveness of any interventions that can be used in the management of external root resorption in permanent teeth.
The following electronic databases were searched: the Cochrane Oral Health Group Trials Register (to 14 October 2015), the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library, 2015, Issue 9), MEDLINE via OVID (1946 to 14 October 2015) and EMBASE via OVID (1980 to 14 October 2015). We searched the US National Institutes of Health Trials Register (http://clinicaltrials.gov) and the WHO Clinical Trials Registry Platform for ongoing trials. No restrictions were placed on the language or date of publication when searching the electronic databases.
We included randomised controlled trials of permanent teeth with any type of external root resorption, which has been confirmed by clinical and radiological examination, comparing one type of intervention (root canal medications and canal filling, splinting or extraction of teeth or the surgical removal of any relevant pathology) with another, or with placebo or no treatment.
Two review authors screened search records independently. Full papers were obtained for potentially relevant trials. If data had been extracted, the statistical guidelines set out in the Cochrane Handbook would have been followed.
No randomised controlled trials that met the inclusion criteria were identified. However, we identified one ongoing study that is potentially relevant to this review and will be assessed when it is published.
AUTHORS' CONCLUSIONS: We were unable to identify any reports of randomised controlled trials regarding the efficacy of different interventions for the management of external root resorption. In view of the lack of reliable evidence on this topic, clinicians must decide on the most appropriate means of managing this condition according to their clinical experience with regard to patient-related factors. There is a need for well designed and conducted clinical trials on this topic, which conform to the CONSORT statement (www.consort-statement.org/).
牙根外吸收是一种病理过程，在受到多种机械或化学刺激（如感染、压力、创伤或正畸牙齿移动）后容易发生。虽然主要通过影像学检查发现，但在某些情况下，牙根吸收也可通过临床症状（如疼痛、肿胀和牙齿松动）来识别。治疗方案因具体情况而异，旨在解决吸收的原因并促进吸收性病变的再生。
评估可用于治疗恒牙牙根外吸收的任何干预措施的有效性。
检索了以下电子数据库：Cochrane口腔健康组试验注册库（截至2015年10月14日）、Cochrane对照试验中央注册库（CENTRAL）（《Cochrane图书馆》，2015年第9期）、通过OVID检索的MEDLINE（1946年至2015年10月14日）以及通过OVID检索的EMBASE（1980年至2015年10月14日）。我们检索了美国国立卫生研究院试验注册库（http://clinicaltrials.gov）和世界卫生组织临床试验注册平台以查找正在进行的试验。检索电子数据库时对语言或出版日期没有限制。
我们纳入了经临床和影像学检查确诊的任何类型牙根外吸收的恒牙随机对照试验，比较一种干预措施（根管用药和根管充填、牙齿固定或拔除或手术切除任何相关病变）与另一种干预措施，或与安慰剂或不治疗的效果。
两位综述作者独立筛选检索记录。获取了可能相关试验的全文。如果已提取数据，将遵循Cochrane手册中规定的统计指南。
未识别出符合纳入标准的随机对照试验。然而，我们确定了一项正在进行的研究，该研究可能与本综述相关，待发表时将进行评估。
我们未能找到关于不同干预措施治疗牙根外吸收疗效的随机对照试验报告。鉴于该主题缺乏可靠证据，临床医生必须根据他们在患者相关因素方面的临床经验来决定管理这种情况的最合适方法。需要开展关于该主题的设计良好且实施得当的符合CONSORT声明（www.consort-statement.org/）的临床试验。
