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Perioperative myocardial infarction/injury after noncardiac surgery.

作者信息

Puelacher Christian, Lurati-Buse Giovanna, Singeisen Hélène, Dang Minh, Cuculi Florim, Müller Christian

机构信息

Cardiology and Anaesthesia, University Hospital Basel, Switzerland.

出版信息

Swiss Med Wkly. 2015 Nov 24;145:w14219. doi: 10.4414/smw.2015.14219. eCollection 2015.

Abstract

Cardiovascular complications, particularly perioperative myocardial infarction/injury, seem to be major contributors to mortality after noncardiac surgery. With surgical procedures being very frequent (900 000/year in Switzerland), perioperative myocardial injury is common in everyday clinical practice. Over 80% of patients experiencing perioperative myocardial injury do not report symptoms. Therefore perioperative myocardial injury remains undiagnosed and untreated. Moreover, its silent presentation results in limited awareness among both clinicians and the public. Despite being largely asymptomatic, perioperative myocardial injury increases 30-day mortality nearly 10-fold. This review aims to increase the awareness of perioperative myocardial injury/infarction and give an overview of the emerging evidence, including pathophysiology, clinical presentation, prevention, and potential future treatments.

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