检测人类凝固酶阴性葡萄球菌中超级抗原的存在情况。
Determining the Presence of Superantigens in Coagulase Negative Staphylococci from Humans.
作者信息
Stach Christopher S, Vu Bao G, Schlievert Patrick M
机构信息
Department of Microbiology, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America.
出版信息
PLoS One. 2015 Nov 23;10(11):e0143341. doi: 10.1371/journal.pone.0143341. eCollection 2015.
Superantigens (SAgs) are important virulence factors in S. aureus. Recent studies identified their presence in animal coagulase-negative staphylococci (CNS). The emergence of human-associated SAg+ CNS would mark a prodigious shift in virulence capabilities. We examined CNS isolates from healthy human nares and diseased individuals, and determined that no known SAgs were present.
超抗原（SAgs）是金黄色葡萄球菌中的重要毒力因子。最近的研究发现它们存在于动物凝固酶阴性葡萄球菌（CNS）中。与人类相关的超抗原阳性CNS的出现将标志着毒力能力发生巨大转变。我们检测了来自健康人鼻腔和患病个体的CNS分离株，确定不存在已知的超抗原。
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