Koshenkov Vadim P, Broucek Joe, Kaufman Howard L
Division of Surgical Oncology, Rutgers Cancer Institute of New Jersey, 195 Little Albany St., Suite 3001, New Brunswick, NJ, 08901, USA.
Cancer Treat Res. 2016;167:149-79. doi: 10.1007/978-3-319-22539-5_6.
The surgical management of melanoma has undergone considerable changes over the past several decades, as new strategies and treatments have become available. Surgeons play a pivotal role in all aspects of melanoma care: diagnostic, curative, and palliative. There is a high potential for cure in patients with early-stage melanoma and the selection of an appropriate operation is very important for this reason. Staging the nodal basin has become widespread since the adoption of sentinel lymph node biopsy (SLNB) for the management of melanoma. This operation provides the best prognostic information that is currently available for patients with melanoma. The surgeon plays a central role in the palliation of symptoms resulting from nodal disease and metastases, as melanoma has a propensity to spread to almost any site in the body.
在过去几十年中,随着新的策略和治疗方法的出现,黑色素瘤的外科治疗发生了相当大的变化。外科医生在黑色素瘤治疗的各个方面都发挥着关键作用:诊断、治愈性治疗和姑息治疗。早期黑色素瘤患者有很高的治愈潜力,因此选择合适的手术非常重要。自从采用前哨淋巴结活检(SLNB)来管理黑色素瘤以来,对区域淋巴结进行分期已变得很普遍。该手术为黑色素瘤患者提供了目前可得的最佳预后信息。由于黑色素瘤有扩散到身体几乎任何部位的倾向,外科医生在缓解由区域淋巴结疾病和转移引起的症状方面起着核心作用。