• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

黑色素瘤的外科治疗

Surgical Management of Melanoma.

作者信息

Koshenkov Vadim P, Broucek Joe, Kaufman Howard L

机构信息

Division of Surgical Oncology, Rutgers Cancer Institute of New Jersey, 195 Little Albany St., Suite 3001, New Brunswick, NJ, 08901, USA.

出版信息

Cancer Treat Res. 2016;167:149-79. doi: 10.1007/978-3-319-22539-5_6.

DOI:10.1007/978-3-319-22539-5_6
PMID:26601862
Abstract

The surgical management of melanoma has undergone considerable changes over the past several decades, as new strategies and treatments have become available. Surgeons play a pivotal role in all aspects of melanoma care: diagnostic, curative, and palliative. There is a high potential for cure in patients with early-stage melanoma and the selection of an appropriate operation is very important for this reason. Staging the nodal basin has become widespread since the adoption of sentinel lymph node biopsy (SLNB) for the management of melanoma. This operation provides the best prognostic information that is currently available for patients with melanoma. The surgeon plays a central role in the palliation of symptoms resulting from nodal disease and metastases, as melanoma has a propensity to spread to almost any site in the body.

摘要

在过去几十年中,随着新的策略和治疗方法的出现,黑色素瘤的外科治疗发生了相当大的变化。外科医生在黑色素瘤治疗的各个方面都发挥着关键作用:诊断、治愈性治疗和姑息治疗。早期黑色素瘤患者有很高的治愈潜力,因此选择合适的手术非常重要。自从采用前哨淋巴结活检(SLNB)来管理黑色素瘤以来,对区域淋巴结进行分期已变得很普遍。该手术为黑色素瘤患者提供了目前可得的最佳预后信息。由于黑色素瘤有扩散到身体几乎任何部位的倾向,外科医生在缓解由区域淋巴结疾病和转移引起的症状方面起着核心作用。

相似文献

1
Surgical Management of Melanoma.黑色素瘤的外科治疗
Cancer Treat Res. 2016;167:149-79. doi: 10.1007/978-3-319-22539-5_6.
2
Sentinel lymph node biopsy from the vantage point of an oncologic surgeon.从肿瘤外科医生的角度看前哨淋巴结活检。
Clin Dermatol. 2009 Nov-Dec;27(6):594-6. doi: 10.1016/j.clindermatol.2008.09.017.
3
Sentinel lymph node biopsy in cutaneous melanoma: a case-control study.皮肤黑色素瘤前哨淋巴结活检:一项病例对照研究。
Ann Surg Oncol. 2007 Dec;14(12):3566-74. doi: 10.1245/s10434-007-9606-2. Epub 2007 Oct 9.
4
[The role of surgery in the treatment of cutaneous melanoma].[手术在皮肤黑色素瘤治疗中的作用]
Praxis (Bern 1994). 2011 Jul 27;100(15):911-6. doi: 10.1024/1661-8157/a000613.
5
Sentinel-node biopsy or nodal observation in melanoma.黑色素瘤的前哨淋巴结活检或淋巴结观察
N Engl J Med. 2006 Sep 28;355(13):1307-17. doi: 10.1056/NEJMoa060992.
6
Sentinel lymph node biopsy in melanoma: controversies and current guidelines.黑色素瘤前哨淋巴结活检:争议与现行指南
Future Oncol. 2014 Feb;10(3):429-42. doi: 10.2217/fon.13.245.
7
Pathobiology of the sentinel node.前哨淋巴结的病理生物学
Curr Opin Oncol. 2008 Mar;20(2):190-5. doi: 10.1097/CCO.0b013e3282f46d70.
8
Patterns of initial recurrence and prognosis after sentinel lymph node biopsy and selective lymphadenectomy for melanoma.黑色素瘤前哨淋巴结活检及选择性淋巴结清扫术后的初始复发模式及预后
Plast Reconstr Surg. 2003 Aug;112(2):486-97. doi: 10.1097/01.PRS.0000070989.23469.1F.
9
Surgical treatment of malignant melanoma.恶性黑色素瘤的外科治疗
Surg Clin North Am. 2003 Feb;83(1):109-56. doi: 10.1016/S0039-6109(02)00205-0.
10
Sentinel lymph node biopsy in melanoma patients.黑色素瘤患者前哨淋巴结活检。
J Eur Acad Dermatol Venereol. 2010 Sep;24(9):1005-12. doi: 10.1111/j.1468-3083.2010.03581.x. Epub 2010 Feb 10.

引用本文的文献

1
Rethinking Lymphadenectomy in Cutaneous Melanoma: From Routine Practice to Selective Indication: A Narrative Review.重新思考皮肤黑色素瘤的淋巴结清扫术:从常规做法到选择性指征:一项叙述性综述
Medicina (Kaunas). 2025 Sep 22;61(9):1722. doi: 10.3390/medicina61091722.
2
Proximal Femoral Replacement or Revision Stem Hemiarthroplasty for Metastatic Disease of the Proximal Femur-Is There Any Notable Difference?股骨近端置换术或翻修柄半髋关节置换术治疗股骨近端转移性疾病——有显著差异吗?
J Am Acad Orthop Surg Glob Res Rev. 2025 Jul 29;9(8). doi: 10.5435/JAAOSGlobal-D-24-00243. eCollection 2025 Aug 1.
3
M1 macrophage-derived exosomal microRNA-29c-3p suppresses aggressiveness of melanoma cells via ENPP2.
M1巨噬细胞衍生的外泌体微小RNA-29c-3p通过ENPP2抑制黑色素瘤细胞的侵袭性。
Cancer Cell Int. 2024 Sep 28;24(1):325. doi: 10.1186/s12935-024-03512-0.
4
Optically Guided High-Frequency Ultrasound Shows Superior Efficacy for Preoperative Estimation of Breslow Thickness in Comparison with Multispectral Imaging: A Single-Center Prospective Validation Study.与多光谱成像相比,光学引导高频超声在术前评估Breslow厚度方面显示出更高的疗效:一项单中心前瞻性验证研究。
Cancers (Basel). 2023 Dec 28;16(1):157. doi: 10.3390/cancers16010157.
5
CDK12 is hyperactivated and a synthetic-lethal target in BRAF-mutated melanoma.CDK12 在 BRAF 突变型黑色素瘤中被过度激活并成为合成致死靶点。
Nat Commun. 2022 Oct 29;13(1):6457. doi: 10.1038/s41467-022-34179-8.
6
Multispectral Imaging Algorithm Predicts Breslow Thickness of Melanoma.多光谱成像算法可预测黑色素瘤的 Breslow 厚度。
J Clin Med. 2021 Dec 30;11(1):189. doi: 10.3390/jcm11010189.
7
A Solitary Melanoma Metastasis Confined to the Submandibular Gland.局限于下颌下腺的孤立性黑色素瘤转移灶。
Case Rep Oncol. 2021 Jun 18;14(2):957-962. doi: 10.1159/000516796. eCollection 2021 May-Aug.
8
Anticancer Activity of Two Novel Hydroxylated Biphenyl Compounds toward Malignant Melanoma Cells.两种新型羟基联苯化合物对恶性黑素瘤细胞的抗癌活性。
Int J Mol Sci. 2021 May 26;22(11):5636. doi: 10.3390/ijms22115636.
9
Chondroitin polymerizing factor (CHPF) promotes development of malignant melanoma through regulation of CDK1.软骨素聚合因子 (CHPF) 通过调节 CDK1 促进恶性黑色素瘤的发展。
Cell Death Dis. 2020 Jul 1;11(7):496. doi: 10.1038/s41419-020-2526-9.
10
Association between tumor-infiltrating lymphocytes and sentinel lymph node positivity in thin melanoma.薄型黑色素瘤中肿瘤浸润淋巴细胞与前哨淋巴结阳性之间的关联
An Bras Dermatol. 2019 Jan-Feb;94(1):47-51. doi: 10.1590/abd1806-4841.20197414.