Rosa A, Atzeri A, Putzu D, Scano P
Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, Km 4.5 SS 554, 09042 Monserrato, CA, Italy.
Department of Chemical and Geological Sciences, University of Cagliari, Cittadella Universitaria, SS 554, Km 4.5, 09042 Monserrato, Cagliari, Italy.
Food Funct. 2016 Jan;7(1):202-11. doi: 10.1039/c5fo01202c.
The effect of a diet enriched with mullet bottarga on the lipid profile (total lipids, total cholesterol, unsaturated fatty acids, α-tocopherol, and hydroperoxides) of plasma, liver, kidney, brain, and perirenal adipose tissues of healthy rats was investigated. Rats fed a 10% bottarga enriched-diet for 5 days showed body weights and tissue total lipid and cholesterol levels similar to those of animals fed control diet. Univariate and multivariate results showed that bottarga enriched-diet modified the fatty acid profile in all tissues, except brain. Significant increases of n-3 PUFA, particularly EPA, were observed together with a 20:4 n-6 decrease in plasma, liver, and kidney. Perirenal adipose tissue showed a fat accumulation that reflected the diet composition. The overall data suggest that mullet bottarga may be considered as a natural bioavailable source of n-3 PUFA and qualify it as a traditional food product with functional properties and a potential functional ingredient for preparation of n-3 PUFA enriched foods.
研究了富含鲻鱼鱼籽酱的饮食对健康大鼠血浆、肝脏、肾脏、大脑和肾周脂肪组织的脂质谱（总脂质、总胆固醇、不饱和脂肪酸、α-生育酚和氢过氧化物）的影响。喂食10%富含鱼籽酱饮食5天的大鼠，其体重以及组织总脂质和胆固醇水平与喂食对照饮食的动物相似。单变量和多变量结果表明，富含鱼籽酱的饮食改变了除大脑外所有组织中的脂肪酸谱。在血浆、肝脏和肾脏中观察到n-3多不饱和脂肪酸显著增加，尤其是二十碳五烯酸（EPA），同时20:4 n-6减少。肾周脂肪组织出现了反映饮食组成的脂肪堆积。总体数据表明，鲻鱼鱼籽酱可被视为n-3多不饱和脂肪酸的天然生物可利用来源，并使其有资格成为具有功能特性的传统食品以及制备富含n-3多不饱和脂肪酸食品的潜在功能成分。
