Ondrasík M
Baillieres Clin Rheumatol. 1989 Apr;3(1):205-10. doi: 10.1016/s0950-3579(89)80045-7.
Caplan's syndrome is characterized by the presence of seropositive rheumatoid arthritis associated with a specific form of pneumoconiosis, consisting of multiple, well-defined homogeneous rounded opacities on chest X-ray. It develops especially in miners working in anthracite coal-mines and in persons exposed to silica and asbestos. In the development of the disease, genetic factors are considered to play an important role by influencing immunological reactivity of the organism exposed to various heteroantigens.
卡普兰综合征的特征是血清阳性类风湿性关节炎与一种特定形式的尘肺病相关，胸部X线表现为多个边界清晰的均匀圆形阴影。它尤其在无烟煤矿工以及接触二氧化硅和石棉的人群中发生。在该疾病的发展过程中，遗传因素被认为通过影响接触各种异种抗原的机体的免疫反应性而发挥重要作用。
