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[局限性盐依赖性水源性荨麻疹:一例报告]

[Localized salt-dependent aquagenic urticaria: A case report].

作者信息

Margerin F, Wettlé C, Merklen-Djafri C, Cribier B

机构信息

Service de dermatologie, hôpital civil, 1, place de l'Hôpital, BP 426, 67000 Strasbourg, France.

Service de dermatologie, hôpital civil, 1, place de l'Hôpital, BP 426, 67000 Strasbourg, France.

出版信息

Ann Dermatol Venereol. 2015 Dec;142(12):771-5. doi: 10.1016/j.annder.2015.10.582. Epub 2015 Nov 25.

Abstract

BACKGROUND

Aquagenic urticaria is a rare but well-known form of physical urticaria mainly affecting young women. It is characterised by the appearance of erythematous and pruritic plaques a few minutes after initial contact with water and irrespective of temperature. The physiopathology of this condition remains poorly understood. Herein, we report a case of localised aquagenic urticaria occurring solely on contact with seawater.

PATIENTS AND METHODS

A 32-year-old woman reported onset of erythematous and pruritic plaques, confined to the neck and lower part of the face, several minutes after the start of bathing in seawater. Skin tests were carried out by applying wet compresses soaked in seawater (37°C for 30 min) to the areas in which the skin reaction usually occurred. A control test using a compress soaked in fresh water was carried out under identical conditions. An urticaria reaction was noted in the areas in contact with seawater, but no reaction was seen in the areas coming into contact with fresh water. Antihistamines taken on the days of bathing proved ineffective.

DISCUSSION

A number of similar cases have been reported in the literature, enabling the characterisation of this particular form of aquagenic urticaria and allowing its principal characteristics to be defined. It appears to be dependent solely on the salt content of the water. It is reported by young women while bathing in seawater. The urticaria plaques show a predilection for the neck and lower part of the face, as in our case, as well as the shoulders on occasion. The efficacy of antihistamines is inconsistent. The prevalence of this as yet poorly known entity is doubtless underreported.

摘要

背景

水源性荨麻疹是一种罕见但广为人知的物理性荨麻疹,主要影响年轻女性。其特征是在初次接触水后几分钟内出现红斑和瘙痒性斑块,且与水温无关。这种疾病的生理病理学仍知之甚少。在此,我们报告一例仅在接触海水时发生的局限性水源性荨麻疹病例。

患者与方法

一名32岁女性报告称,在开始海水浴几分钟后,颈部和面部下部出现了红斑和瘙痒性斑块。通过将浸泡在海水中(37°C,30分钟)的湿敷料敷在通常出现皮肤反应的部位进行皮肤试验。在相同条件下使用浸泡在淡水中的敷料进行对照试验。在与海水接触的部位出现了荨麻疹反应,但在与淡水接触的部位未观察到反应。在沐浴当天服用的抗组胺药无效。

讨论

文献中已报道了一些类似病例,从而能够对这种特殊形式的水源性荨麻疹进行特征描述并确定其主要特征。它似乎仅取决于水的盐含量。年轻女性在海水浴时会出现这种情况。如我们的病例所示,荨麻疹斑块好发于颈部和面部下部,偶尔也会出现在肩部。抗组胺药的疗效并不一致。这种尚不为人熟知的疾病的患病率无疑被低估了。

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