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在淋巴细胞诱导的血管生成试验中,派尔集合淋巴结和其他淋巴组织细胞诱发的小鼠局部移植物抗宿主反应。

Local graft-versus-host reaction in mice evoked by Peyer's patch and other lymphoid tissue cells tested in a lymphocyte-induced angiogenesis assay.

作者信息

Kamiński M, Kamińska G, Majewski S

出版信息

Folia Biol (Praha). 1978;24(2):104-10.

PMID:26612
Abstract

The competence of murine Peyer's patch cells to evoke a local GVH reaction was compared with that displayed by lymphoid cells of spleen, lymph nodes, thymus, bone marrow, peritoneal cavity and peripheral blood. The local GVH reaction was assessed in a lymphocyte-induced angiogenesis assay in which an intradermal injection of lymphoid cells results in a new blood vessel formation at the injection site, and the number of vessels corresponds to the number of the immunocompetent cells injected. Peyer's patch cells were capable of mounting a local GVH reaction of intensity comparable to that evoked by the corresponding number of thymus cells or a four times lower number of spleen cells. The highest activity was exhibited by lymph node and peripheral blood cells while bone marrow cells were the least active. A striking increase in angiogenic response was observed after X-irradiation of the recipients with 700R.

摘要

将小鼠派伊尔结细胞引发局部移植物抗宿主反应(GVH反应)的能力,与脾脏、淋巴结、胸腺、骨髓、腹腔和外周血的淋巴细胞所表现出的能力进行了比较。在淋巴细胞诱导的血管生成试验中评估局部GVH反应,在该试验中皮内注射淋巴细胞会导致注射部位形成新的血管,血管数量与注射的免疫活性细胞数量相对应。派伊尔结细胞能够引发强度与相应数量的胸腺细胞或数量低四倍的脾细胞所引发的局部GVH反应相当的反应。淋巴结和外周血细胞表现出最高活性,而骨髓细胞活性最低。用700伦琴的X射线照射受体后,观察到血管生成反应显著增加。

相似文献

1
Local graft-versus-host reaction in mice evoked by Peyer's patch and other lymphoid tissue cells tested in a lymphocyte-induced angiogenesis assay.在淋巴细胞诱导的血管生成试验中,派尔集合淋巴结和其他淋巴组织细胞诱发的小鼠局部移植物抗宿主反应。
Folia Biol (Praha). 1978;24(2):104-10.
2
Intrahepatic lymphoid tissue graft: course of the Gvh reaction induced by Peyer's patches.肝内淋巴组织移植:派尔集合淋巴结诱导的移植物抗宿主反应过程
Biomedicine. 1975 Apr 30;23(4):139-43.
3
Heterotopic transplantation of syngeneic lymphoid tissues in mice. The ability of graft repopulation cells to enhance cell-mediated immunity as measured in the lymphocyte-induced angiogenesis assay.小鼠同基因淋巴组织的异位移植。在淋巴细胞诱导的血管生成试验中测定移植物再填充细胞增强细胞介导免疫的能力。
Arch Immunol Ther Exp (Warsz). 1981;29(4):525-7.
4
Peyer's patch cells. Absence of graft-versus-host reactivity in mice and rats.派尔集合淋巴结细胞。小鼠和大鼠中无移植物抗宿主反应性。
Lab Invest. 1972 Oct;27(4):427-33.
5
Functional characteristics of Peyer's patch lymphoid cells. IV. Effect of antigen feeding on the frequency of antigen-specific B cells.派尔集合淋巴结淋巴细胞的功能特性。IV. 经口给予抗原对抗原特异性B细胞频率的影响。
J Immunol. 1977 Mar;118(3):992-7.
6
Functional studies of Peyer's patches: evidence for their participation in intestinal immune responses.派尔集合淋巴结的功能研究:其参与肠道免疫反应的证据
J Immunol. 1975 Jun;114(6):1757-60.
7
[Peyer's patches and cellular immunity].[派尔集合淋巴结与细胞免疫]
Biol Gastroenterol (Paris). 1975 Jan-Feb;8(1):73-86.
8
Differential effects of vasoactive intestinal peptide, substance P, and somatostatin on immunoglobulin synthesis and proliferations by lymphocytes from Peyer's patches, mesenteric lymph nodes, and spleen.血管活性肠肽、P物质和生长抑素对派伊尔结、肠系膜淋巴结和脾脏淋巴细胞免疫球蛋白合成及增殖的不同作用。
J Immunol. 1986 Jan;136(1):152-6.
9
Differences in the migration of B and T lymphocytes: organ-selective localization in vivo and the role of lymphocyte-endothelial cell recognition.B淋巴细胞和T淋巴细胞迁移的差异:体内器官选择性定位及淋巴细胞与内皮细胞识别的作用
J Immunol. 1982 Feb;128(2):844-51.
10
Effect of sublethal ionizing radiation on rat Peyer's patch lymphocytes.亚致死剂量电离辐射对大鼠派伊尔结淋巴细胞的影响。
Radiat Res. 1984 Jul;99(1):151-64.

引用本文的文献

1
Human peripheral blood T lymphocyte subpopulations isolated on the basis of their affinity for sheep red blood cells differ in angiogenesis-inducing capability.根据对绵羊红细胞的亲和力分离出的人外周血T淋巴细胞亚群,其诱导血管生成的能力有所不同。
Clin Exp Immunol. 1981 Nov;46(2):327-31.
2
Presence of natural killer cells in Peyer's patches of the mouse.小鼠派尔集合淋巴结中自然杀伤细胞的存在。
Experientia. 1980 Dec 15;36(12):1418. doi: 10.1007/BF01960135.