Choi Daniel K, Schmidt Mary Lou
Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of Illinois at Chicago College of Medicine, 840 South Wood Street, MC 856, Chicago, IL 60612, USA.
Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of Illinois at Chicago College of Medicine, 840 South Wood Street, MC 856, Chicago, IL 60612, USA.
Oral Maxillofac Surg Clin North Am. 2016 Feb;28(1):127-38. doi: 10.1016/j.coms.2015.08.004.
Cancers of the head and neck in children represent a heterogeneous group of malignancies requiring a variety of treatment modalities. In many instances of childhood head and neck cancers, chemotherapy will be required for treatment, often in conjunction with surgery and/or radiation therapy. Chemotherapy in children with head and neck cancers poses unique challenges in terms of immediate as well as long-term toxicities. This article focuses on the common chemotherapeutic agents, with a particular focus on early and late effects, used in the treatment of children with head and neck cancers.
儿童头颈部癌症是一组异质性恶性肿瘤，需要多种治疗方式。在许多儿童头颈部癌症病例中，治疗通常需要化疗，且常与手术和/或放射治疗联合使用。儿童头颈部癌症的化疗在近期和长期毒性方面都带来了独特的挑战。本文重点介绍用于治疗儿童头颈部癌症的常见化疗药物，特别关注早期和晚期效应。
