Vokes E E
University of Chicago, Cancer Research Center, Illinois, USA.
Oncology (Williston Park). 1997 Sep;11(9 Suppl 9):27-30.
The treatment of head and neck cancer has traditionally consisted of surgery with postoperative radiation therapy. Chemotherapy has been reserved for palliation. In recent years, induction chemotherapy has been shown to allow for larynx preservation in patients with laryngeal or hypopharyngeal cancer. Concomitant chemoradiotherapy has been shown to provide a statistically significant survival benefit in selected studies and recent meta-analyses. In patients with nasopharyngeal cancer, the use of cisplatin and concomitant radiation therapy results in a marked survival benefit.
传统上，头颈癌的治疗包括手术及术后放射治疗。化疗一直仅用于姑息治疗。近年来，诱导化疗已被证明可使喉癌或下咽癌患者保留喉功能。在一些选定的研究和近期的荟萃分析中，同步放化疗已显示出具有统计学意义的生存获益。在鼻咽癌患者中，使用顺铂并同步放疗可带来显著的生存获益。
