Rognstad R
Lemontree Research Institute, Sylmar, CA 91342.
Metabolism. 1989 Jul;38(7):619-24. doi: 10.1016/0026-0495(89)90097-8.
Ignoring the reality of glucose in equilibrium glucose-6P cycling in the liver in vivo produces large potential errors in the isotopic quantitation of percentage contributions of direct and indirect pathways of glycogen synthesis and of hepatic glucose output.
忽略肝脏中葡萄糖与葡萄糖-6-磷酸在体内处于平衡循环这一现实,会在糖原合成直接和间接途径以及肝脏葡萄糖输出的百分比贡献的同位素定量方面产生巨大的潜在误差。