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膀胱过度活动症:临床特征、尿动力学参数及治疗

Underactive Bladder: Clinical Features, Urodynamic Parameters, and Treatment.

作者信息

Hoag Nathan, Gani Johan

机构信息

Department of Urology, Austin Hospital, University of Melbourne, Melbourne, Australia.

出版信息

Int Neurourol J. 2015 Sep;19(3):185-9. doi: 10.5213/inj.2015.19.3.185. Epub 2015 Sep 22.

DOI:10.5213/inj.2015.19.3.185
PMID:26620901
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4582091/
Abstract

PURPOSE

Underactive bladder is a complex clinical condition that remains poorly understood due to limited literature. This study aimed to determine its prevalence among patients with voiding dysfunction, presenting symptoms, risk factors, urodynamic findings, and ongoing treatment.

METHODS

A retrospective chart review of consecutive urodynamic studies performed on voiding dysfunction between 2012 and 2014 was conducted to identify patients with detrusor underactivity. Detrusor underactivity was defined by a bladder contractility index of less than 100. Charts and urodynamic tracings were examined for patient demographics, suspected risk factors, presenting symptoms, urodynamic parameters, and treatment undertaken. Descriptive statistics were utilized to analyze the data.

RESULTS

The prevalence of detrusor underactivity in this study was 23% (79 of 343). Average age of the patients was 59.2 years (range, 19-90 years). Women represented 68.4% (54 of 79) of the patients. The most common reported symptoms were urinary urgency (63.3%), weak stream (61.0%), straining (57.0%), nocturia (48.1%), and urinary frequency (46.8%). Prior pelvic surgery and prior back surgery were noted in 40.5% and 19.0% of the patients, respectively. The most common management was intermittent self-catheterization in 54.4%, followed by observation/conservative treatment in 25.3% and sacral neuromodulation in 12.7%.

CONCLUSIONS

Although underactive bladder is a common condition, its precise diagnosis and treatment remain a challenge. Its symptoms significantly overlap with those of other bladder disorders, and hence, urodynamic evaluation is particularly useful in identifying patients with impaired detrusor contractility. This will help prevent mismanagement of patients with surgery or medical therapy, as that may worsen their condition. Much work needs to be done to better understand this condition and establish optimal management of patients.

摘要

目的

膀胱活动低下是一种复杂的临床病症,由于文献有限,目前对其了解甚少。本研究旨在确定其在排尿功能障碍患者中的患病率、呈现的症状、危险因素、尿动力学检查结果以及正在进行的治疗情况。

方法

对2012年至2014年间连续进行的针对排尿功能障碍的尿动力学研究进行回顾性病历审查,以识别逼尿肌活动低下的患者。逼尿肌活动低下的定义为膀胱收缩力指数小于100。检查病历和尿动力学记录,了解患者的人口统计学信息、疑似危险因素、呈现的症状、尿动力学参数以及所采取的治疗措施。采用描述性统计分析数据。

结果

本研究中逼尿肌活动低下的患病率为23%(343例中的79例)。患者的平均年龄为59.2岁(范围为19 - 90岁)。女性占患者的68.4%(79例中的54例)。报告的最常见症状为尿急(63.3%)、尿流无力(61.0%)、用力排尿(57.0%)、夜尿症(48.1%)和尿频(46.8%)。分别有40.5%和19.0%的患者有既往盆腔手术史和既往背部手术史。最常见的治疗方法是间歇性自我导尿,占54.4%,其次是观察/保守治疗,占25.3%,骶神经调节占12.7%。

结论

尽管膀胱活动低下是一种常见病症,但其准确诊断和治疗仍然是一项挑战。其症状与其他膀胱疾病的症状有显著重叠,因此,尿动力学评估对于识别逼尿肌收缩功能受损的患者特别有用。这将有助于防止对患者进行不当的手术或药物治疗,因为这可能会使他们的病情恶化。要更好地了解这种病症并建立对患者的最佳管理,仍有许多工作要做。

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Eur Urol. 2015 Sep;68(3):351-3. doi: 10.1016/j.eururo.2015.02.030. Epub 2015 Mar 11.
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Bladder underactivity.膀胱活动低下
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