尿路结石患者中骨质疏松症的性别表现
Gender Representation of Osteoporosis in Patients with Urolithiasis.
作者信息
Bijelic Radojka, Balaban Milorad, Milicevic Snjezana
机构信息
Health Center, Banja Luka, Bosnia and Herzegovina.
Pan-European University "Apeiron", Faculty of Health Sciences, Banja Luka, Bosnia and Herzegovina.
出版信息
Med Arch. 2015 Oct;69(5):331-3. doi: 10.5455/medarh.2015.69.331-333. Epub 2015 Oct 4.
INTRODUCTION
A great number of clinical studies has indicated that the patients with calcium urolithiasis have a reduced mineral bone density.
AIM
The aim of our research was to establish representation of osteoporosis, by measuring mineral bone density using the DEXA method, in patients with calcium urolithiasis, by gender.
MATERIAL AND METHODS
The research was a prospective one, performed at the University Hospital of the Clinical Center of Banja Luka, at the Urology Clinic and Clinic for Endocrinology, Diabetes and Metabolic Diseases. The material in this research were the patients divided into two groups: a working group (the patients suffering from calcium urolithiasis) and a control group (the patients without calcium urolithiasis). One hundred and twenty (120) patients were included in both these groups, divided in three age subgroups: 20-40, 40-60 and over 60. The total working group consisted of 63 men (52.2%) and 57 (47.5%) women. In the control group, the number of women was 72 (60%) and 48 (40%) of men. Establishing of mineral bone density at L2-L4 of lumbal spine vertebrae and hip was done for the patients in both these groups, using DEXA method.
RESULTS
Analysis of mineral bone density using DEXA method in patients by gender of working and control groups has shown that osteoporosis and osteopenia in patients of the working group is significantly more present in women (14% and 22.8%) compared to men (1.6% and 17.5%). When compared by gender in the control group, osteoporosis was present a lot more in women (36.1%) compared to men (2.1%). When observed for the total sample of both the working and control group, there was a statistically significant difference (p<0,01) related to gender structure, where the share of women with osteoporosis/osteopenia was significantly higher (36.1%) compared to men (4.2%).
CONCLUSION
Representation of osteoporosis in women with urolithiasis, particularly of older age, is very expressed and this is why prevention measures should start as soon as possible, so as to avoid severe complications of this illness.
引言
大量临床研究表明，钙结石患者的骨矿物质密度降低。
目的
我们研究的目的是通过使用双能X线吸收法（DEXA）测量骨矿物质密度，按性别确定钙结石患者中骨质疏松症的情况。
材料与方法
该研究为前瞻性研究，在巴尼亚卢卡临床中心大学医院的泌尿外科诊所和内分泌、糖尿病及代谢疾病诊所进行。本研究的材料为分为两组的患者：工作组（患有钙结石的患者）和对照组（无钙结石的患者）。这两组均纳入了120名患者，分为三个年龄亚组：20 - 40岁、40 - 60岁和60岁以上。工作组共有63名男性（52.2%）和57名女性（47.5%）。对照组中女性有72名（60%），男性有48名（40%）。使用DEXA方法对这两组患者的腰椎L2 - L4和髋部进行骨矿物质密度测定。
结果
通过DEXA方法按性别对工作组和对照组患者的骨矿物质密度分析表明，工作组中女性的骨质疏松症和骨质减少症（分别为14%和22.8%）比男性（分别为1.6%和17.5%）更为显著。在对照组中按性别比较，女性的骨质疏松症（36.1%）比男性（2.1%）更为常见。当观察工作组和对照组的总样本时，与性别结构相关存在统计学显著差异（p<0.01），其中患有骨质疏松症/骨质减少症的女性比例（36.1%）明显高于男性（4.2%）。
结论
结石病女性，尤其是老年女性中骨质疏松症的情况非常明显，这就是为什么预防措施应尽早开始，以避免该疾病的严重并发症。
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