Lin Lawrence C-L, Brown Frank L H
Department of Physics, University of California, Santa Barbara, California 93106-9530, and Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106-9510.
J Chem Theory Comput. 2006 May;2(3):472-83. doi: 10.1021/ct050293s.
Two previously introduced simulation algorithms for the dynamics of elastic membrane sheets embedded in a fluid medium are extended to account for inhomogeneous hydrodynamic environments. We calculate the height autocorrelation function for a lipid bilayer randomly pinned to a flat substrate and the influence of fluid confinement by the spectrin cytoskeleton on short wavelength membrane undulations of the human red blood cell. Altering the hydrodynamic environment of the membrane leads to significant changes in dynamics, and we discuss these effects in the context of recent experiments.
两种先前引入的用于模拟嵌入流体介质中的弹性膜片动力学的算法得到了扩展，以考虑非均匀流体动力学环境。我们计算了随机固定在平坦基底上的脂质双层的高度自相关函数，以及血影蛋白细胞骨架对人类红细胞短波长膜波动的流体限制影响。改变膜的流体动力学环境会导致动力学的显著变化，我们将在近期实验的背景下讨论这些影响。
