Chen Qing, Wu Chi, Gao Yang, Chen Lijuan, Liu Yuejian
Department of Respiration, Hospital of University of Electronic Science and Technology of China & Sichuan Provincial People's Hospital Chengdu 610072, Sichuan, China.
Int J Clin Exp Med. 2015 Sep 15;8(9):16613-9. eCollection 2015.
This study aimed to evaluate the effect of psychotic therapy on patients with chronic obstructive pulmonary disease (COPD) complicated with anxiety-depression disorder by Hamilton Depression Scale (HAMD), Hamilton Anxiety Scale (HAMA), COPD Assessment Test (CAT) and modified British Medical research Council (mMRC). Thirty-five patients with COPD were evaluated by pulmonary physicians with CAT and mMRC. They were further evaluated with HAMD and HAMA by psychologists and diagnosed and grouped into group B and D according to the Global initiative for chronic Obstructive Lung Disease (GOLD) version 2014. Patients were given psychotic therapy and followed up for at least 1 month. Comparison and analysis were performed with clinical data before and after treatment. Fourteen patients were subscribed into B group, while 21 patients were subscribed into D group, accounting for 40% and 60% respectively. After psychotic therapy, the HAMA and MAMD score of patients in both groups improved significantly (P<0.05). The CAT and Mmrc score of 8 patients in B group improved as A, while 10 patients in D group improved as B. The longest follow-up was 12 months. Symptoms were significantly alleviated after combined respiratory and psychotic therapy. COPD complicated with anxiety-depression is of high prevalence. The psychosomatic problems usually aggravate respiratory symptoms. Make better use of the evaluation methods such as HAMA, HAMA, CAT, mMRC may facilitate the treatment for patients.
本研究旨在通过汉密尔顿抑郁量表（HAMD）、汉密尔顿焦虑量表（HAMA）、慢性阻塞性肺疾病评估测试（CAT）和改良英国医学研究委员会（mMRC）评估心理治疗对慢性阻塞性肺疾病（COPD）合并焦虑抑郁障碍患者的疗效。35例COPD患者由肺科医生用CAT和mMRC进行评估。他们由心理学家用HAMD和HAMA进一步评估，并根据2014年版慢性阻塞性肺疾病全球倡议（GOLD）进行诊断和分组为B组和D组。给予患者心理治疗并随访至少1个月。对治疗前后的临床资料进行比较和分析。14例患者归入B组，21例患者归入D组，分别占40%和60%。心理治疗后，两组患者的HAMA和MAMD评分均显著改善（P<0.05）。B组8例患者的CAT和Mmrc评分改善为A，D组10例患者改善为B。最长随访时间为12个月。联合呼吸和心理治疗后症状明显缓解。COPD合并焦虑抑郁的患病率较高。身心问题通常会加重呼吸道症状。更好地利用HAMA、HAMA、CAT、mMRC等评估方法可能有助于患者的治疗。
