Faccenda F, Rubba P, Vaccaro O, Carbone L, Pauciullo P, Riccardi G
Institute of Internal Medicine and Metabolic Disease, 2nd Medical School, University of Naples, Italy.
Artery. 1989;16(4):189-207.
Reproducibility of noninvasive ultrasound methods for vascular diagnosis was studied in 36 patients with Insulin Dependent Diabetes Mellitus. The vascular examination included a) the measurement of ankle systolic arterial pressure and ankle/arm pressure index (c.w. Doppler), b) Echo-Doppler examination of iliac arteries with measurement of maximum systolic frequency, systolic spectrum width and diastolic reverse flow component. A grading of iliac artery stenosis was also performed. The examination was repeated after one month according to a blind protocol. The coefficients of variation were as follows: 8% for ankle pressure; 8% for ankle/arm pressure index; 9% for the maximum systolic frequency; 18% for the spectrum width and 15% for the reverse flow component. The reproducibility of the grading of iliac artery stenosis based on the combined use of the three Echo-Doppler parametres was measured by the Kendall coefficient (W = 0.865). These results confirm that non invasive methods are suitable and reliable for investigating vascular disease in diabetic patients. Accurate estimates of reproducibility are essential pre-requisites for the planning of studies on the natural history of vascular disease and on progression-regression of arterial lesions.
对36例胰岛素依赖型糖尿病患者的血管诊断无创超声方法的可重复性进行了研究。血管检查包括：a）测量踝部收缩期动脉压和踝/臂压力指数（连续波多普勒）；b）对髂动脉进行回声多普勒检查，测量最大收缩期频率、收缩期频谱宽度和舒张期反向血流成分。同时还对髂动脉狭窄进行分级。根据盲法方案，一个月后重复检查。变异系数如下：踝部压力为8%；踝/臂压力指数为8%；最大收缩期频率为9%；频谱宽度为18%；反向血流成分为15%。基于三种回声多普勒参数联合使用的髂动脉狭窄分级的可重复性通过肯德尔系数测量（W = 0.865）。这些结果证实，无创方法适用于且可靠地用于研究糖尿病患者的血管疾病。对可重复性的准确估计是规划血管疾病自然史和动脉病变进展-消退研究的基本前提。
