肥大细胞分化的调控
Regulation of mast cell differentiation.
作者信息
Kitamura Y, Fujita J
出版信息
Bioessays. 1989 Jun;10(6):193-6. doi: 10.1002/bies.950100604.
PMID:2662964
Abstract
Mast cells are a unique class of blood cell. Unlike most blood cells, undifferentiated precursors of mast cells migrate in the bloodstream, invade tissues, proliferate there and then differentiate. Even after differentiation, some mast cells may proliferate extensively. Differentiation of mast cells is regulated by both diffusible growth factors and direct contact with fibroblasts.
摘要
肥大细胞是一类独特的血细胞。与大多数血细胞不同，未分化的肥大细胞前体在血液中迁移，侵入组织，在那里增殖，然后分化。即使在分化之后，一些肥大细胞仍可能大量增殖。肥大细胞的分化受可扩散生长因子和与成纤维细胞直接接触的双重调节。
Zotero 插件