Turna Jasmine, Grosman Kaplan Keren, Anglin Rebecca, Van Ameringen Michael
MacAnxiety Research Centre, McMaster University, Hamilton, Ontario, Canada.
MiNDS Neuroscience Graduate Program, McMaster University, Hamilton, Ontario, Canada.
Depress Anxiety. 2016 Mar;33(3):171-8. doi: 10.1002/da.22454. Epub 2015 Dec 2.
The gut microbiome has become a topic of major interest as of late, with a new focus specifically on psychiatric disorders. Recent studies have revealed that variations in the composition of the gut microbiota may influence anxiety and mood and vice versa. Keeping the concept of this bidirectional "microbiota-gut-brain" axis in mind, this review aims to shed light on how these findings may also be implicated in obsessive-compulsive disorder (OCD); potentially outlining a novel etiological pathway of interest for future research in the field.
近年来,肠道微生物群已成为一个备受关注的话题,尤其聚焦于精神疾病。最近的研究表明,肠道微生物群组成的变化可能会影响焦虑和情绪,反之亦然。基于这种双向“微生物群-肠道-大脑”轴的概念,本综述旨在阐明这些发现如何也可能与强迫症(OCD)有关;这可能为该领域未来的研究勾勒出一条新的病因学途径。