Ahmed F N, Stence N V, Mirsky D M
From the Department of Radiology (F.N.A.), University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Department of Radiology (N.V.S., D.M.M.), Children's Hospital Colorado, Aurora, Colorado.
AJNR Am J Neuroradiol. 2016 Apr;37(4):726-9. doi: 10.3174/ajnr.A4602. Epub 2015 Dec 3.
With the use of high-resolution MR imaging techniques, we have increasingly observed anomalies of the hypothalamus characterized by a band of tissue spanning the third ventricle between the hypothalami, often without associated clinical sequelae. Historically, hypothalamic anomalies are highly associated with symptoms referable to a hypothalamic hamartoma, midline congenital disorder, hypothalamic-pituitary dysfunction, or seizures, with very few asymptomatic patients reported. The interhypothalamic tissue described in our cohort was observed incidentally through the routine acquisition of high-resolution T1WI. No referable symptoms were identified in most of the study group. In the appropriate patient population in which associated symptoms are absent, the described hypothalamic anomalies may be incidental and should not be misdiagnosed as hypothalamic hamartomas.
通过使用高分辨率磁共振成像技术，我们越来越多地观察到下丘脑异常，其特征是一条组织带横跨下丘脑之间的第三脑室，通常没有相关的临床后遗症。从历史上看，下丘脑异常与下丘脑错构瘤、中线先天性疾病、下丘脑 - 垂体功能障碍或癫痫相关的症状高度相关，报告的无症状患者很少。我们队列中描述的下丘脑间组织是通过常规采集高分辨率T1WI偶然发现的。在大多数研究组中未发现相关症状。在没有相关症状的合适患者群体中，所描述的下丘脑异常可能是偶然的，不应误诊为下丘脑错构瘤。
