Lipworth B J, McMurray J J, Clark R A, Struthers A D
Dept of Clinical Pharmacology, Ninewells Hospital and Medical School, Dundee, UK.
Eur Respir J. 1989 Jun;2(6):586-8.
We describe the first case of de novo asthma following treatment with the angiotensin converting enzyme (ACE) inhibitor captopril. Despite drug withdrawal there was evidence of persistent airways obstruction and bronchial hyperreactivity. This suggests the possibility that ACE inhibitors may uncover an asthmatic tendency in patients with pre-existing bronchial hyperreactivity.
我们描述了首例在使用血管紧张素转换酶（ACE）抑制剂卡托普利治疗后新发哮喘的病例。尽管停用了药物，但仍有持续性气道阻塞和支气管高反应性的证据。这表明ACE抑制剂可能会在已有支气管高反应性的患者中揭示出哮喘倾向。
