使用二氧化碳和空气注入法在非镇静结肠镜检查后评估腹围和唾液淀粉酶活性。

Evaluation of abdominal circumference and salivary amylase activities after unsedated colonoscopy using carbon dioxide and air insufflations.

作者信息

Kiriyama Shinsuke, Naitoh Hiroshi, Fukuchi Minoru, Yuasa Kazuhisa, Horiuchi Katsuhiko, Fukasawa Takaharu, Tabe Yuichi, Yamauchi Hayato, Suzuki Masaki, Yoshida Tomonori, Saito Yutaka, Kuwano Hiroyuki

机构信息

Department of Surgery, Gunma Chuo Hospital, Gunma.

Department of Gastroenterology, Gunma Chuo Hospital, Gunma.

出版信息

J Dig Dis. 2015 Dec;16(12):747-51. doi: 10.1111/1751-2980.12302.

DOI:10.1111/1751-2980.12302

PMID:26639093

Abstract

OBJECTIVE

To assess and compare abdominal distention and stress in unsedated colonoscopy using carbon dioxide (CO2 ) and air insufflations.

METHODS

Two hundred and five patients underwent colonoscopic examinations without sedation using either CO2 or air insufflation. Abdominal circumference and salivary amylase (sAMY) activities before and 0 and 15 min after colonoscopy were measured by a nurse who was blinded to the grouping of the patients.

RESULTS

In all, 102 and 103 patients were randomly recruited in the CO2 and air insufflation groups, respectively. sAMY activities before and 0 and 15 min after colonoscopy were not significantly different between the two groups. Abdominal circumference measured immediately and 15 min after colonoscopy was significantly smaller in CO2 insufflation group than in the air insufflation group (81.2 cm vs 84.0 cm, and 79.7 cm vs 83.6 cm, respectively; P <0.05). The increasing ratio of abdominal circumference immediately after colonoscopy was not significantly different between the two groups; however, the ratio at 15 min after colonoscopy using CO2 insufflation was significantly lower than that in the air insufflation group (1.007 vs 1.028, P <0.001).

CONCLUSION

sAMY activities after unsedated colonoscopy using CO2 insufflation were not improved; however, CO2 insufflation decreases abdominal circumference after colonoscopy compared with air insufflation.

摘要

目的

评估和比较在未使用镇静剂的结肠镜检查中，使用二氧化碳（CO₂）充气和空气充气时的腹胀情况及应激反应。

方法

205例患者在未使用镇静剂的情况下接受结肠镜检查，分别采用CO₂或空气充气。由对患者分组不知情的护士测量结肠镜检查前、检查结束时及检查后15分钟的腹围和唾液淀粉酶（sAMY）活性。

结果

CO₂充气组和空气充气组分别随机招募了102例和103例患者。两组患者结肠镜检查前、检查结束时及检查后15分钟的sAMY活性无显著差异。CO₂充气组结肠镜检查结束时及检查后15分钟测量的腹围明显小于空气充气组（分别为81.2 cm对84.0 cm，以及79.7 cm对83.6 cm；P<0.05）。两组结肠镜检查结束后即刻腹围的增加比例无显著差异；然而，使用CO₂充气时结肠镜检查后15分钟的比例显著低于空气充气组（1.007对1.028，P<0.001）。