Department of Cardiovascular Surgery, Chiba-Nishi General Hospital, 107-1 Kanegasaku, Matsudo-shi, Chiba-Ken, Chiba, 270-2251, Japan.
Gen Thorac Cardiovasc Surg. 2021 Aug;69(8):1174-1184. doi: 10.1007/s11748-020-01573-2. Epub 2021 Jan 5.
This study analyzed the experience of a single institution with minimally invasive mitral valve repair (MIMVr) via a right mini-thoracotomy (RT), including short and mid-term morbidity and mortality as surgical outcomes, and rates of reoperation. Late follow-up findings regarding mitral regurgitation (MR) were also assessed.
Between January 2014 and January 2020, a total of 141 consecutive patients underwent MIMVr for mitral regurgitation at our institution via an RT, with late follow-up results (median 35 ± 15 months) available for 129 (91.4%). Findings regarding surgical approach, complications, reoperations, and late survival were examined. Late echocardiographic results showing recurrence of MR after mitral repair were also noted. Survival, freedom from reoperation, and recurrent MR (grade > 2) were evaluated by Kaplan-Meier analysis.
Mean age was 63.9 ± 14.3 years, mean ejection fraction was 66.9 ± 10.4%, and 2 patients (1.6%) underwent a reoperation. Concomitant procedures included atrial fibrillation ablation (18%), tricuspid valve surgery (16%). None (0%) experienced intraoperative conversion to sternotomy. A learning curve was observed as the number of cases increased. Overall in-hospital mortality and stroke incidence were both 0%. Freedom from recurrent MR (grade > 2) at 1, 3, and 5 years was 99.2, 94.9, and 94.9%, respectively, while freedom from reoperation at 1, 3, and 5 years after mitral valve repair was 98.4, 98.4, and 98.4%, respectively.
Early and mid-term results of MIMVr were satisfactory, with low rates of perioperative morbidity and recurrent MR, as well as reoperation and death. Furthermore, the protocols for patient selection and surgical approach were considered to be appropriate.
本研究通过右胸小切口(RT)分析单中心微创二尖瓣修复术(MIMVr)的经验,包括手术结果的短期和中期发病率和死亡率,以及再次手术的发生率。还评估了晚期随访时二尖瓣反流(MR)的发现。
2014 年 1 月至 2020 年 1 月,我院共对 141 例连续二尖瓣反流患者行 MIMVr 术,其中 129 例(91.4%)获得晚期随访结果(中位数 35±15 个月)。检查了手术方法、并发症、再次手术和晚期生存情况。还记录了二尖瓣修复后 MR 复发的晚期超声心动图结果。通过 Kaplan-Meier 分析评估生存、无再次手术和复发性 MR(等级>2)。
平均年龄为 63.9±14.3 岁,平均射血分数为 66.9±10.4%,2 例(1.6%)患者行再次手术。同时进行的手术包括心房颤动消融术(18%)、三尖瓣手术(16%)。无(0%)患者术中转为正中开胸。随着病例数的增加,观察到学习曲线。总的院内死亡率和卒中发生率均为 0%。1、3 和 5 年时无复发性 MR(等级>2)的生存率分别为 99.2%、94.9%和 94.9%,1、3 和 5 年时二尖瓣修复后无再次手术的生存率分别为 98.4%、98.4%和 98.4%。
MIMVr 的早期和中期结果令人满意,围手术期发病率和复发性 MR 以及再次手术和死亡的发生率较低。此外,患者选择和手术方法的方案被认为是合适的。