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心脏手术领域的突破:微创二尖瓣修复联合三尖瓣修复和/或其他同期手术

Pushing boundaries in cardiac surgery: minimally invasive mitral valve repair combined with tricuspid valve repair and/or other concomitant procedures.

作者信息

Stelzmueller Marie-Elisabeth, Zilberszac Robert, Rosenhek Raphael, Hutschala Doris, Kappel Sabine, Lassnig Andrea, Laufer Guenther, Zimpfer Daniel, Wisser Wilfried

机构信息

University Clinic of Cardiac Surgery, Medical University Vienna, Vienna, Austria.

Department of Cardiology, Medical University Vienna, Vienna, Austria.

出版信息

Front Cardiovasc Med. 2024 Aug 9;11:1407591. doi: 10.3389/fcvm.2024.1407591. eCollection 2024.

Abstract

INTRODUCTION

Minimally invasive mitral valve repair/replacement has emerged as a widely accepted surgical approach for managing mitral valve disorders. Continuous technological progress has contributed to the refinement of this procedure, leading to improved safety, decreased surgical trauma, and faster recovery times. Despite these advancements, there remains a scarcity of data concerning minimally invasive complex mitral valve repair surgeries when combined with additional procedures.

METHODS

Between November 2008 and December 2022, 153 patients underwent an operation using a minimally invasive technique. All patients underwent mitral valve surgery for severe mitral valve insufficiency/stenosis in combination with at least one additional procedure for tricuspid valve repair ( = 52, 34%), patent foramen ovale or atrial septal defect closure ( = 34, 22.2%), left atrial appendage occlusion ( = 25, 16.3%), or electrophysiological procedure ( = 101, 66.0%). Two concomitant procedures were conducted in 98 patients (64.1%), three concomitant procedures in 49 patients (32%), and four concomitant procedures in 6 patients (3.9%).

RESULTS

Surgical success was achieved in 99.3% of the patients ( = 152), one patient required a revision of the mitral valve repair on the first postoperative day due to systolic anterior motion phenomenon. Mitral valve repair was performed in 136 patients (88.9%), while 15 patients (9.8%) received a mitral valve replacement as per a preoperative decision due to severe mitral valve stenosis, and two patients (1.3%) underwent other mitral valve procedures. Therapeutic success in treating atrial fibrillation was achieved in 86 patients (85.1%) of the 101 who received an additional maze-procedure. The 30-day mortality rate was 0.7%, with one patient succumbing to respiratory failure. Neurological complications occurred in 7 patients (4.6%). Freedom from reoperation was calculated as 98% at 5-year follow-up and 96.5% at 10-year follow-up.

CONCLUSION

Minimally invasive mitral valve surgery, even when performed alongside concomitant procedures, stands out as a reproducible and safe technique with outstanding outcomes. It is imperative to advance towards the next frontier in minimally invasive surgery, encouraging experienced surgeons to undertake more complex procedures using minimally invasive approaches. These results help envision extending the boundaries of minimally invasive surgery by performing complex mitral valve procedures and associated interventions entirely through endoscopic means in suitable patients.

摘要

引言

微创二尖瓣修复/置换术已成为治疗二尖瓣疾病广泛接受的手术方法。持续的技术进步推动了该手术的完善,提高了安全性,减少了手术创伤,缩短了恢复时间。尽管有这些进展,但关于微创复杂二尖瓣修复手术与其他手术联合时的数据仍然匮乏。

方法

2008年11月至2022年12月期间,153例患者接受了微创手术。所有患者均因严重二尖瓣关闭不全/狭窄接受二尖瓣手术,并至少接受一项其他手术,包括三尖瓣修复(n = 52,34%)、卵圆孔未闭或房间隔缺损封堵(n = 34,22.2%)、左心耳封堵(n = 25,16.3%)或电生理手术(n = 101,66.0%)。98例患者(64.1%)进行了两项联合手术,49例患者(32%)进行了三项联合手术,6例患者(3.9%)进行了四项联合手术。

结果

99.3%的患者(n = 152)手术成功,1例患者因收缩期前向运动现象在术后第一天需要对二尖瓣修复进行翻修。136例患者(88.9%)进行了二尖瓣修复,15例患者(9.8%)因严重二尖瓣狭窄根据术前决定接受了二尖瓣置换,2例患者(1.3%)接受了其他二尖瓣手术。在接受附加迷宫手术的101例患者中,86例(85.1%)房颤治疗取得成功。30天死亡率为0.7%,1例患者死于呼吸衰竭。7例患者(4.6%)发生神经并发症。5年随访时再次手术率为98%,10年随访时为96.5%。

结论

微创二尖瓣手术,即使与联合手术一起进行,也是一种可重复且安全的技术,效果显著。必须朝着微创手术的下一个前沿迈进,鼓励有经验的外科医生采用微创方法进行更复杂的手术。这些结果有助于设想通过在合适的患者中完全通过内镜手段进行复杂二尖瓣手术及相关干预来扩展微创手术的边界。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1df2/11341354/70b0ae6094e4/fcvm-11-1407591-g001.jpg

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