Bruno Vito D, Celmeta Bleri, Viva Tommaso, Bisogno Arturo, Miceli Antonio, Glauber Mattia
Department of Minimally Invasive Cardiac Surgery - IRCCS Galeazzi - Sant'Ambrogio Hospital, Milan, Italy.
Innovations (Phila). 2024 Nov-Dec;19(6):660-665. doi: 10.1177/15569845241289429. Epub 2024 Oct 29.
Minimally invasive surgery determines shorter postoperative hospital length of stay (LOS) even in cardiac surgery. Potential preoperative factors affecting LOS are still not known in minimally invasive heart valve surgery (MIVS). We aimed to identify preoperative variables influencing prolonged LOS in MIVS.
We reviewed 189 patients who underwent MIVS via minithoracotomy at our institution. Prolonged LOS was defined as more than 7 postoperative days. Poisson and logistic regression were used to screen the predictors.
The mean postoperative LOS was 9.13 days, and 64 patients (33.9%) experienced a prolonged LOS. These patients were older, more frequently in New York Heart Association (NYHA) class III or IV, showed worse left ventricular ejection function (LVEF), and had a higher incidence of reoperation and chronic kidney disease (CKD). At univariate analysis, the most significant preoperative factors affecting prolonged LOS were age (odds ratio [OR] = 1.04), NYHA class III or IV (OR = 3.03), reduced LVEF (OR = 3.22), CKD (OR = 2.7), and redo surgery (OR = 3.6). After adjustment, the most significant preoperative factors predicting prolonged LOS were age (OR = 1.03, 95% CI: 1.01 to 1.06, = 0.02) and redo surgery (OR = 3.33, 95% CI: 1.29 to 8.9, = 0.01).
The most important factors affecting prolonged LOS after MIVS were represented by age and redo surgery, although other preoperative characteristics such as reduced LVEF, NYHA class III or IV, and CKD play a significant role in delaying recovery after MIVS. Further larger studies are needed to better identify potential preoperative predictors of prolonged LOS after MIVS.
即使在心脏手术中,微创手术也能缩短术后住院时间(LOS)。在微创心脏瓣膜手术(MIVS)中,影响住院时间的潜在术前因素仍不明确。我们旨在确定影响MIVS术后住院时间延长的术前变量。
我们回顾了在我院接受经小切口开胸MIVS手术的189例患者。术后住院时间延长定义为术后超过7天。采用泊松回归和逻辑回归筛选预测因素。
术后平均住院时间为9.13天,64例患者(33.9%)术后住院时间延长。这些患者年龄较大,纽约心脏协会(NYHA)心功能分级更常为III级或IV级,左心室射血功能(LVEF)较差,再次手术和慢性肾脏病(CKD)的发生率较高。单因素分析显示,影响术后住院时间延长的最显著术前因素为年龄(比值比[OR]=1.04)、NYHA III级或IV级(OR=3.03)、LVEF降低(OR=3.22)、CKD(OR=2.7)和再次手术(OR=3.6)。调整后,预测术后住院时间延长的最显著术前因素为年龄(OR=1.03,95%可信区间:1.01至1.06,P=0.02)和再次手术(OR=3.33,95%可信区间:1.29至8.9,P=0.01)。
影响MIVS术后住院时间延长的最重要因素是年龄和再次手术,尽管其他术前特征如LVEF降低、NYHA III级或IV级以及CKD在MIVS术后恢复延迟中也起重要作用。需要进一步开展更大规模的研究,以更好地确定MIVS术后住院时间延长的潜在术前预测因素。