Lellouche François, Delorme Mathieu, Bussières Jean, Ouattara Alexandre
Institut Universitaire de Cardiologie et Pneumologie de Québec, Faculté de Médecine, Université Laval, Ville de Québec, Canada.
Institut Universitaire de Cardiologie et Pneumologie de Québec, Faculté de Médecine, Université Laval, Ville de Québec, Canada; CHU de Bordeaux, Service d'Anesthésie-Réanimation II, Univ. Bordeaux, Adaptation Cardiovasculaire à l'ischémie, U1034 et INSERM, Adaptation Cardiovasculaire à l'ischémie, U1034, F-33600 Pessac, France.
Best Pract Res Clin Anaesthesiol. 2015 Sep;29(3):381-95. doi: 10.1016/j.bpa.2015.08.006. Epub 2015 Sep 4.
Recent data promote the utilization of prophylactic protective ventilation even in patients without acute respiratory distress syndrome (ARDS), and especially after cardiac surgery. The implementation of specific perioperative ventilatory strategies in patients undergoing cardiac surgery can improve both respiratory and extra-pulmonary outcomes. Protective ventilation is not limited to tidal volume reduction. The major components of ventilatory management include assist-controlled mechanical ventilation with low tidal volumes (6-8 mL kg(-1) of predicted body weight) associated with higher positive end-expiratory pressure (PEEP), limitation of fraction of inspired oxygen (FiO2), ventilation maintenance during cardiopulmonary bypass, and finally recruitment maneuvers. In order for such strategies to be fully effective, they should be integrated into a multimodal approach beginning from the induction and continuing over the postoperative period.
近期数据表明,即使对于没有急性呼吸窘迫综合征(ARDS)的患者,尤其是心脏手术后的患者,预防性保护性通气也值得采用。对接受心脏手术的患者实施特定的围手术期通气策略,可改善呼吸和肺外结局。保护性通气并不局限于降低潮气量。通气管理的主要组成部分包括采用低潮气量(预测体重的6 - 8 mL·kg⁻¹)并联合较高呼气末正压(PEEP)的辅助控制机械通气、限制吸入氧分数(FiO₂)、体外循环期间的通气维持,以及最后的肺复张手法。为使这些策略充分有效,应从诱导期开始并持续至术后阶段,将其纳入多模式方法。