基于肠降血糖素的治疗与急性胰腺炎相关：大型随机对照试验的荟萃分析。
Incretin-based therapies are associated with acute pancreatitis: Meta-analysis of large randomized controlled trials.
机构信息
Schulich School of Medicine and Dentistry, Western University, 1465 Richmond St, London, ON N6G 2M1, Canada.
Peter Boris Centre for Addictions Research, St Joseph's Healthcare Hamilton, 50 Charlton Avenue East, Hamilton, ON L8N 4A6, Canada.
出版信息
Diabetes Res Clin Pract. 2015 Dec;110(3):e13-7. doi: 10.1016/j.diabres.2015.10.014. Epub 2015 Oct 23.
Previous studies have offered weak and conflicting evidence regarding the impact of incretin-based oral antihyperglycemic agents on risk of acute pancreatitis. This meta-analysis of three recent mega-trials found an 82% increase in the odds of acute pancreatitis with the use of these agents compared to usual care (95% CI, 1.17-2.82).
先前的研究对于肠降血糖素类口服抗高血糖药物对急性胰腺炎风险的影响提供了微弱且相互矛盾的证据。这项对三项最近大型试验的荟萃分析发现，与常规治疗相比，这些药物的使用使急性胰腺炎的几率增加了 82%（95%CI，1.17-2.82）。
Zotero 插件