Rasoulinejad Seyed Ahmad, Hajian-Tilaki Karimollah, Mehdipour Elnaz
Department of Ophthalmology, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran.
Department of Biostatistics and Epidemiology, Babol University of Medical Sciences, Babol, Iran.
Caspian J Intern Med. 2015 Fall;6(4):224-8.
Information regarding the frequency and severity of eye involvement in diabetic patients and its risk factors can be useful for prevention and treatment. This study aimed to determine the prevalence of diabetic retinopathy and its associated risk factors in diabetic patients who referred to teaching hospitals in Babol, Mazandaran.
In this study a total of 1562 patients with the definite diagnosis of diabetes mellitus were chosen and referred to the eye clinic of Shahid Beheshti and Ayatollah Rouhani Hospitals of Babol during 2006-2010. Information about age, duration of diabetes, hypertension family history of diabetes, history of other organs involvement, BMI and laboratory findings were recorded. Retinopathy was classified according to early treatment of diabetic retinopathy study. Data were collected and analyzed.
Of the 1562 patients, 357 (22.9%) were males and 1205 (77.1%) were females. The mean age was 54.6±10.6 years, diabetic retinopathy was found in 990 (64.1%) patients, the frequency of non-proliferative diabetic retinopathy was 37.3% and proliferative was 26.8%.Age, duration of diabetes, FBS, HbA1C, BUN, Cr, Hb were significantly different between the patient's with diabetic retinopathy and no diabetic retinopathy (p<0.05). No relationship was found between smoking, gender, hypertension and serum lipid profile.
Poor diabetes control, anemia and nephropathy were the most associated factors of diabetic retinopathy but hypertension BMI smoking, dyslipidemia and gender showed no association.
了解糖尿病患者眼部受累的频率、严重程度及其危险因素,有助于预防和治疗。本研究旨在确定转诊至马赞德兰省巴博勒市教学医院的糖尿病患者中糖尿病视网膜病变的患病率及其相关危险因素。
本研究共选取1562例确诊糖尿病患者,于2006 - 2010年转诊至巴博勒市沙希德·贝赫什提医院和阿亚图拉·鲁哈尼医院眼科门诊。记录患者的年龄、糖尿病病程、糖尿病家族史、其他器官受累史、体重指数(BMI)及实验室检查结果。根据糖尿病视网膜病变早期治疗研究对视网膜病变进行分类。收集并分析数据。
1562例患者中,男性357例(22.9%),女性1205例(77.1%)。平均年龄为54.6±10.6岁,990例(64.1%)患者发现糖尿病视网膜病变,非增殖性糖尿病视网膜病变发生率为37.3%,增殖性为26.8%。糖尿病视网膜病变患者与无糖尿病视网膜病变患者在年龄、糖尿病病程、空腹血糖(FBS)、糖化血红蛋白(HbA1C)、血尿素氮(BUN)、肌酐(Cr)、血红蛋白(Hb)方面存在显著差异(p<0.05)。未发现吸烟、性别、高血压与血脂谱之间存在关联。
糖尿病控制不佳、贫血和肾病是糖尿病视网膜病变最相关的因素,但高血压、BMI、吸烟、血脂异常和性别未显示出相关性。