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[伴有多发性静脉血栓形成和急性肾功能不全的阵发性夜间血红蛋白尿。病例描述]

[Paroxysmal nocturnal hemoglobinuria with multiple venous thrombosis and acute renal insufficiency. Description of a case].

作者信息

Tedde R, Sechi L A, Marigliano A, Loriga V

机构信息

Universita di Sassari, Ospedale SS. Annunziata.

出版信息

Minerva Med. 1989 Jun;80(6):615-8.

PMID:2664576
Abstract

Oral anticoagulants were administered to a young woman suffering from P.N.H. after the development of portal vein thrombosis. She interrupted the treatment and developed multiple splanchnic thromboses followed by acute renal failure, from which she recovered four weeks later. Although the pathogenetic mechanism could include renal vascular microthrombosis, the possibility of renal ischemic damage due to massive blood pooling within the splanchnic district is discussed.

摘要

一名患有阵发性夜间血红蛋白尿(PNH)的年轻女性在发生门静脉血栓形成后接受了口服抗凝剂治疗。她中断了治疗,随后出现了多发性内脏血栓形成,继之发生急性肾衰竭,四周后康复。尽管发病机制可能包括肾血管微血栓形成,但本文讨论了由于内脏区域大量血液淤积导致肾缺血性损伤的可能性。

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