Bi Sheng, Fan Jia, Dong Jing, Liu Qun
Department of Neurology, Second Hospital, Jilin University, Changchun, China.
Neurosciences (Riyadh). 2011 Jul;16(3):267-9.
Cerebral venous sinus thrombosis caused by paroxysmal nocturnal hemoglobinuria is uncommon. Our case is a 44-year-old woman who presented with a 2 day history of headaches, nausea, and seizures followed by a Todd`s paresis; she had been diagnosed as paroxysmal nocturnal hemoglobinuria for 4 years. A magnetic resonance venography revealed extensive thrombosis of the cerebral venous sinus. She received antithrombotic treatment with a good outcome. We highlight paroxysmal nocturnal hemoglobinuria as the reason for the cerebral venous sinus thrombosis. The treatment of cerebral venous sinus thrombosis caused by paroxysmal nocturnal hemoglobinuria should be individualized.
阵发性夜间血红蛋白尿引起的脑静脉窦血栓形成并不常见。我们的病例是一名44岁女性，有2天头痛、恶心和癫痫发作史，随后出现陶德麻痹；她被诊断为阵发性夜间血红蛋白尿已有4年。磁共振静脉造影显示脑静脉窦广泛血栓形成。她接受了抗血栓治疗，效果良好。我们强调阵发性夜间血红蛋白尿是脑静脉窦血栓形成的原因。阵发性夜间血红蛋白尿引起的脑静脉窦血栓形成的治疗应个体化。
