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远端胆管癌和胰腺导管腺癌：假定一种共同的肿瘤实体。

Distal bile duct carcinomas and pancreatic ductal adenocarcinomas: postulating a common tumor entity.

作者信息

Schmuck Rosa B, de Carvalho-Fischer Cynthia V, Neumann Christopher, Pratschke Johann, Bahra Marcus

机构信息

General, Visceral and Transplantation Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.

出版信息

Cancer Med. 2016 Jan;5(1):88-99. doi: 10.1002/cam4.566. Epub 2015 Dec 9.

DOI:10.1002/cam4.566
PMID:26645826
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4708893/
Abstract

The set definition of distal cholangiocarcinomas and adenocarcinomas of the pancreatic head is challenged by their close anatomical relation, similar growth pattern, and corresponding therapeutic outcome. They show a mutual development during embryologic organ formation and share phenotypic characteristics. This review will highlight the similarities with regard to the common origin of their primary organs, histopathological similarities, and modern clinical management. Thus, we propose to subsume those entities under a common superfamily.

摘要

远端胆管癌和胰头腺癌的既定定义受到它们紧密的解剖关系、相似的生长模式及相应治疗结果的挑战。它们在胚胎器官形成过程中相互发展并具有共同的表型特征。本综述将着重阐述它们在主要器官共同起源、组织病理学相似性以及现代临床管理方面的相似之处。因此，我们建议将这些实体归入一个共同的超家族。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43f6/4708893/c272a5ad4ede/CAM4-5-088-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43f6/4708893/ee5219158a36/CAM4-5-088-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43f6/4708893/987abe6dfad6/CAM4-5-088-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43f6/4708893/c272a5ad4ede/CAM4-5-088-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43f6/4708893/ee5219158a36/CAM4-5-088-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43f6/4708893/987abe6dfad6/CAM4-5-088-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43f6/4708893/c272a5ad4ede/CAM4-5-088-g003.jpg

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