Tyle P, Agrawala P
Sandoz Research Institute, Sandoz Pharmaceuticals Corporation, Lincoln, Nebraska 68501.
Pharm Res. 1989 May;6(5):355-61. doi: 10.1023/a:1015967012253.
Phonophoresis is defined as the migration of drug molecules, contained in a contact agent, through the skin under the influence of ultrasound. Several drugs have been introduced into the body by this technique. The design of a phonophoretic drug delivery system is in developmental stages in various research laboratories. Parameters affecting the delivery of drugs by this technique and devices available for drug delivery purposes are discussed in this review.
超声透药疗法的定义是,在超声波的作用下,接触剂中所含的药物分子透过皮肤迁移。已有几种药物通过该技术被导入体内。超声透药给药系统的设计在各个研究实验室中仍处于研发阶段。本综述讨论了影响该技术药物递送的参数以及用于药物递送目的的装置。