Hörner Andreas, Hörner Rosmari, Salla Adenilde, Nunes Melise Silveira, Garzon Litiérri Razia, Rampelotto Roberta Filipini, Martini Rosiéli, Santos Silvana Oliveira dos, Gindri Lívia, Rodrigues Mônica de Abreu, Giacomolli Cláudia
Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brasil.
Department of Clinical and Toxicological Analyses, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brasil.
Sao Paulo Med J. 2015 Sep-Oct;133(5):450-3. doi: 10.1590/1516-3180.2013.79400715. Epub 2015 Mar 17.
Staphylococcal scalded skin syndrome is an exfoliative skin disease. Reports of this syndrome in newborns caused by methicillin-resistant Staphylococcus aureus are rare but, when present, rapid diagnosis and treatment is required in order to decrease morbidity and mortality.
A premature newly born girl weighing 1,520 g, born with a gestational age of 29 weeks and 4 days, developed staphylococcal scalded skin syndrome on the fifth day of life. Cultures on blood samples collected on the first and fourth days were negative, but Pseudomonas aeruginosa and Enterococcus sp. (vancomycin-sensitive) developed in blood cultures performed on the day of death (seventh day), and Pseudomonas aeruginosa and Serratia marcescens were identified in cultures on nasopharyngeal, buttock and abdominal secretions. In addition to these two Gram-negative bacilli, methicillin-resistant Staphylococcus aureus was isolated in a culture on the umbilical stump (seventh day). The diagnosis of staphylococcal scalded skin syndrome was based on clinical criteria.
葡萄球菌性烫伤样皮肤综合征是一种剥脱性皮肤病。耐甲氧西林金黄色葡萄球菌引起的新生儿该综合征报告罕见，但一旦出现，需要快速诊断和治疗以降低发病率和死亡率。
一名出生体重1520克、胎龄29周零4天的早产女婴在出生后第5天患上葡萄球菌性烫伤样皮肤综合征。出生第1天和第4天采集的血样培养结果为阴性，但在死亡当天（第7天）进行的血培养中培养出铜绿假单胞菌和肠球菌属（对万古霉素敏感），在鼻咽、臀部和腹部分泌物培养中鉴定出铜绿假单胞菌和粘质沙雷氏菌。除这两种革兰氏阴性杆菌外，在脐残端培养物（第7天）中分离出耐甲氧西林金黄色葡萄球菌。葡萄球菌性烫伤样皮肤综合征的诊断基于临床标准。
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