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成人人工耳蜗植入者电极与蜗轴距离和电流水平之间的关系

Relationship Between Electrode-to-Modiolus Distance and Current Levels for Adults With Cochlear Implants.

作者信息

Davis Timothy J, Zhang Dongqing, Gifford Rene H, Dawant Benoit M, Labadie Robert F, Noble Jack H

出版信息

Otol Neurotol. 2016 Jan;37(1):31-7. doi: 10.1097/MAO.0000000000000896.

Abstract

HYPOTHESIS

Electrode-to-modiolus distance is correlated with clinically programmed stimulation levels.

BACKGROUND

Conventional wisdom has long supposed a significant relationship between cochlear implant (CI) stimulation levels and electrode-to-modiolus distance; however, to date, no such formal investigation has been completed. Thus, the purpose of this project was to investigate the relationship between stimulation levels and electrode-to-modiolus distance. A strong correlation between the two would suggest that stimulation levels might be used to estimate electrode-to-modiolus geometry.

METHODS

Electrode-to-modiolus distance was determined via CT imaging using validated CI position analysis software in 137 implanted ears from the three manufacturers holding FDA approval in the United States. Analysis included 2,365 total electrodes, with 1,472 from precurved arrays. Distances were compared to clinically programmed C/M levels that were converted to charge units.

RESULTS

Mean modiolar distance with perimodiolar and lateral wall electrodes was 0.47 and 1.15 mm, respectively. Mean suprathreshold charge values were significantly different between each manufacturer. When combining all data, we found a moderate positive correlation (r = 0.367, p < 0.01) that was driven both by the different charge values across companies, and that the company with the highest mean charge values only offers straight electrode arrays. When grouped by electrode type, however, we found a weak correlation (r = 0.12, p < 0.01) for perimodiolar array electrodes only. When considering a single array type from any one manufacturer, only one was observed where distance mildly predicted charge.

CONCLUSION

Our results suggest that electrode distance minimally contributes to the current level required for suprathreshold stimulation.

摘要

假设

电极与蜗轴的距离与临床设定的刺激水平相关。

背景

长期以来,传统观点一直认为人工耳蜗(CI)刺激水平与电极到蜗轴的距离之间存在显著关系;然而,迄今为止,尚未完成此类正式研究。因此,本项目的目的是研究刺激水平与电极到蜗轴距离之间的关系。两者之间的强相关性可能表明刺激水平可用于估计电极到蜗轴的几何结构。

方法

在美国持有FDA批准的三家制造商的137只植入耳中,通过使用经过验证的CI位置分析软件的CT成像来确定电极到蜗轴的距离。分析包括总共2365个电极,其中1472个来自预弯曲阵列。将距离与转换为电荷单位的临床设定的C/M水平进行比较。

结果

蜗周电极和侧壁电极的平均蜗轴距离分别为0.47和1.15毫米。每个制造商之间的平均阈上电荷值存在显著差异。综合所有数据时,我们发现存在中度正相关(r = 0.367,p < 0.01),这是由不同公司的不同电荷值以及平均电荷值最高的公司仅提供直电极阵列所驱动的。然而,按电极类型分组时,我们发现仅蜗周阵列电极存在弱相关性(r = 0.12,p < 0.01)。考虑来自任何一家制造商的单一阵列类型时,仅观察到一例距离对电荷有轻微预测作用的情况。

结论

我们的结果表明电极距离对阈上刺激所需的电流水平贡献极小。

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