Noble Jack H, Gifford René H, Labadie Robert F, Dawant Benoît M
Depts. of Elect. Eng. and Comp. Sci., Vanderbilt University, Nashville, TN 37235, USA.
Med Image Comput Comput Assist Interv. 2012;15(Pt 2):421-8. doi: 10.1007/978-3-642-33418-4_52.
Cochlear implant (CI) surgery is considered standard of care treatment for severe hearing loss. CIs are currently programmed using a one-size-fits-all type approach. Individualized, position-based CI programming schemes have the potential to significantly improve hearing outcomes. This has not been possible because the position of stimulation targets is unknown due to their small size and lack of contrast in CT. In this work, we present a segmentation approach that relies on a weighted active shape model created using microCT scans of the cochlea acquired ex-vivo in which stimulation targets are visible. The model is fitted to the partial information available in the conventional CTs and used to estimate the position of structures not visible in these images. Quantitative evaluation of our method results in Dice scores averaging 0.77 and average surface errors of 0.15 mm. These results suggest that our approach can be used for position-dependent image-guided CI programming methods.
人工耳蜗植入(CI)手术被认为是重度听力损失的标准治疗方法。目前,人工耳蜗采用一刀切的编程方式。基于位置的个性化人工耳蜗编程方案有可能显著改善听力效果。但由于刺激靶点尺寸小且在CT图像中缺乏对比度,其位置未知,所以一直无法实现这一点。在这项工作中,我们提出了一种分割方法,该方法依赖于使用离体获取的耳蜗微CT扫描创建的加权主动形状模型,其中刺激靶点是可见的。该模型与传统CT中可用的部分信息相匹配,并用于估计这些图像中不可见结构的位置。对我们方法的定量评估结果显示,骰子系数平均为0.77,平均表面误差为0.15毫米。这些结果表明,我们的方法可用于基于位置的图像引导人工耳蜗编程方法。