[Therapeutic effectiveness of D-penicillamine in ankylosing arthritis of the spine in relation to the degree of pathological changes in the joints].

On the basis of biochemical indices the anthors assessed the efficacy of a 6-month treatment with D-penicillin in 49 patients with ankylosing arthritis of the spine who did not respond to nonsteroid antiinflammatory drugs. Improvement in the movements of the spine was observed in patients with less marked roentgenological changes.