Woods A J, Antal A, Bikson M, Boggio P S, Brunoni A R, Celnik P, Cohen L G, Fregni F, Herrmann C S, Kappenman E S, Knotkova H, Liebetanz D, Miniussi C, Miranda P C, Paulus W, Priori A, Reato D, Stagg C, Wenderoth N, Nitsche M A
Center for Cognitive Aging and Memory, Institute on Aging, McKnight Brain Institute, Department of Aging and Geriatric Research, Department of Neuroscience, University of Florida, Gainesville, FL, USA.
University Medical Center, Dept. Clinical Neurophysiology, Georg-August-University, Goettingen, Germany.
Clin Neurophysiol. 2016 Feb;127(2):1031-1048. doi: 10.1016/j.clinph.2015.11.012. Epub 2015 Nov 22.
Transcranial electrical stimulation (tES), including transcranial direct and alternating current stimulation (tDCS, tACS) are non-invasive brain stimulation techniques increasingly used for modulation of central nervous system excitability in humans. Here we address methodological issues required for tES application. This review covers technical aspects of tES, as well as applications like exploration of brain physiology, modelling approaches, tES in cognitive neurosciences, and interventional approaches. It aims to help the reader to appropriately design and conduct studies involving these brain stimulation techniques, understand limitations and avoid shortcomings, which might hamper the scientific rigor and potential applications in the clinical domain.
经颅电刺激(tES),包括经颅直流电刺激和交流电刺激(tDCS、tACS),是越来越多地用于调节人类中枢神经系统兴奋性的非侵入性脑刺激技术。在此,我们探讨经颅电刺激应用所需的方法学问题。本综述涵盖经颅电刺激的技术方面,以及诸如脑生理学探索、建模方法、认知神经科学中的经颅电刺激和干预方法等应用。其目的是帮助读者合理设计和开展涉及这些脑刺激技术的研究,理解其局限性并避免可能妨碍科学严谨性及临床领域潜在应用的缺点。