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基于山羊奶的配方奶粉对断奶大鼠发育的影响。

Effects of goat milk-based formula on development in weaned rats.

作者信息

Xu Meihong, Wei Liren, Dai Zhiyong, Zhang Yanchun, Li Yong, Wang Junbo

机构信息

Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, China.

Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety, Peking University, Beijing, China.

出版信息

Food Nutr Res. 2015 Dec 8;59:28610. doi: 10.3402/fnr.v59.28610. eCollection 2015.

Abstract

OBJECTIVE

The aim of this article is to study the effect of goat milk-based formula (GMF) on development in weaned rats.

METHODS

One hundred Sprague-Dawley rats were randomly divided into five groups: control, 20% cow milk-based formula (CMF), and 5%-GMF, 10%-GMF, and 20%-GMF groups.

RESULTS

GMF did play an active role in accelerating body and femur length, but not body weight growth. Compared with the control, GMF had better cognitive, space, and locomotor activity. The level of IFN was increased in GMF groups, as well as the level of IL-2 and TNF was decreased in GMF groups.

CONCLUSION

These results indicate that GMF has an effect on development and immunity improvability in weaned rats.

摘要

目的

本文旨在研究山羊奶配方奶粉(GMF)对断奶大鼠发育的影响。

方法

将100只斯普拉格-道利大鼠随机分为五组:对照组、20%牛奶配方奶粉(CMF)组以及5%-GMF组、10%-GMF组和20%-GMF组。

结果

GMF在加速身体和股骨长度增长方面确实发挥了积极作用,但对体重增长没有影响。与对照组相比,GMF具有更好的认知、空间和运动活动能力。GMF组中IFN水平升高,同时GMF组中IL-2和TNF水平降低。

结论

这些结果表明GMF对断奶大鼠的发育和免疫改善有影响。

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