Xu Meihong, Wang Yibin, Dai Zhiyong, Zhang Yanchun, Li Yong, Wang Junbo
Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, China.
Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety, Peking University, Beijing, China.
Food Nutr Res. 2015 Dec 10;59:28613. doi: 10.3402/fnr.v59.28613. eCollection 2015.
To compare the growth and nutritional status of infants fed goat milk-based formula (GMF) and cow milk-based formula (CMF).
The study was conducted in Beijing, China. It was a double-blind randomized controlled trial. A total of 79 infants aged 0-3 months old were recruited and randomized in GMF or CMF group. The infants were fed the allocated formula to 6 months. The weight, length, and head circumference were measured at the enrolment, 3 and 6 months. The start time and types of solid food were recorded. Blood elements, urinal, and fecal parameters were also tested.
The average weight of infants in the GMF group (mean±SD) was 4.67±0.99 kg and in the CMF group 4.73±1.10 kg at enrolment, and 8.75±0.98 kg (GMF) and 8.92±0.88 kg (CMF) at 6 months. There were no differences in the adjusted intention-to-treat analyses of weight, length, head circumference, and BMI z-scores between the two formula-fed groups over the 6-month study. Similarly, there were no remarkable differences in the timing and types of solid food, blood elements, urinal, and feces parameters, between the GMF and CMF group. No group differences have been shown in bowel motion consistency, duration of crying, ease of settling, or frequency of adverse events.
GMF-provided growth and nutritional outcomes did not differ from those provided by CMF.
比较食用山羊奶配方奶粉（GMF）和牛奶配方奶粉（CMF）的婴儿的生长情况和营养状况。
本研究在中国北京进行。这是一项双盲随机对照试验。共招募了79名0至3个月大的婴儿，并随机分为GMF组或CMF组。这些婴儿食用分配的配方奶粉至6个月。在入组时、3个月和6个月时测量体重、身长和头围。记录固体食物的开始时间和类型。还检测了血液成分、尿液和粪便参数。
GMF组婴儿入组时的平均体重（均值±标准差）为4.67±0.99千克，CMF组为4.73±1.10千克；6个月时，GMF组为8.75±0.98千克，CMF组为8.92±0.88千克。在为期6个月的研究中，两组配方奶粉喂养婴儿在体重、身长、头围和BMI z评分的调整意向性分析中没有差异。同样，GMF组和CMF组在固体食物的时间和类型、血液成分、尿液和粪便参数方面也没有显著差异。在排便稠度、哭闹持续时间、安抚难易程度或不良事件发生频率方面，两组之间没有差异。
GMF提供的生长和营养结果与CMF提供的结果没有差异。
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