Baytak Aysegul Kutluay, Teker Tugce, Duzmen Sehriban, Aslanoglu Mehmet
Department of Chemistry, University of Harran, Sanliurfa 63510, Turkey.
Department of Chemistry, University of Harran, Sanliurfa 63510, Turkey.
Mater Sci Eng C Mater Biol Appl. 2016 Feb;59:368-374. doi: 10.1016/j.msec.2015.10.030. Epub 2015 Oct 22.
An electrochemical sensor was prepared by the modification of a glassy carbon electrode (GCE) with carbon nanotubes (CNTs) and nanoparticles of antimony tin oxide (ATO). The surface layer was characterized by scanning electronmicroscopy (SEM), energy dispersive X-ray diffraction method (EDX) and ATR FT-IR spectroscopy. The proposed electrode was assessed in respect to the electro-oxidation of ractopamine. Compared with a bare GCE and a GCE electrode modified with CNTs, the ATONPs/CNTs/GCE exhibited a great catalytic activity towards the oxidation of ractopamine with a well-defined anodic peak at 600 mV. The current response was linear with the concentration of ractopamine over the range from 10 to 240 nM with a detection limit of 3.3 nM. The proposed electrode enabled the selective determination of ractopamine in the presence of high concentrations of ascorbic acid (AA), dopamine (DA) and uric acid (UA). The proposed electrode was successfully applied for the determination of ractopamine in feed and urine samples. The sensitive and selective determination of ractopamine makes the developed method of great interest for monitoring its therapeutic use and doping control purposes.
通过用碳纳米管（CNTs）和锑锡氧化物（ATO）纳米颗粒修饰玻碳电极（GCE）制备了一种电化学传感器。通过扫描电子显微镜（SEM）、能量色散X射线衍射法（EDX）和衰减全反射傅里叶变换红外光谱（ATR FT-IR）对表面层进行了表征。对所制备的电极进行了莱克多巴胺电氧化方面的评估。与裸玻碳电极和用碳纳米管修饰的玻碳电极相比，ATO纳米颗粒/碳纳米管/玻碳电极对莱克多巴胺的氧化表现出很大的催化活性，在600 mV处有一个明确的阳极峰。电流响应与莱克多巴胺浓度在10至240 nM范围内呈线性关系，检测限为3.3 nM。所制备的电极能够在高浓度抗坏血酸（AA）、多巴胺（DA）和尿酸（UA）存在下选择性测定莱克多巴胺。所制备的电极已成功应用于饲料和尿液样品中莱克多巴胺的测定。莱克多巴胺的灵敏和选择性测定使得所开发的方法对于监测其治疗用途和兴奋剂控制目的具有极大的意义。
