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男性下尿路症状(LUTS)的评估和管理。

Assessment and management of male lower urinary tract symptoms (LUTS).

机构信息

Bristol Urological Institute, Southmead Hospital, Bristol, BS10 5NB, UK.

出版信息

Int J Surg. 2016 Jan;25:164-71. doi: 10.1016/j.ijsu.2015.11.043. Epub 2015 Nov 30.

Abstract

Male lower urinary tract symptoms (LUTS) are common, causing significant bother and impair quality of life. LUTS are a spectrum of symptoms that may or may not be due to benign prostatic obstruction (BPO). LUTS are divided into storage, voiding or post micturition symptoms, which each need to be considered in terms of impact, mechanism and treatment options. In most patients, a mixture of symptoms is present. In order to have a better insight about which symptoms are affecting quality of life, a thorough evaluation should include medical history, examination, validated symptom questionnaires, bladder diary, and flow rate (with post void residual measurement). Other tests, particularly urodynamic tests may be needed to guide treatment selection, particularly for surgery. Management of male LUTS is tailored according to the underlying mechanisms. Different treatment modalities are available according to individual patient preference. These range from watchful waiting, behavioral and dietary modifications, and/or medications - either as monotherapy or in combination. Surgery to relieve BPO may be needed where patients have significant bothersome voiding LUTS, and are willing to accept risks associated with irreversible treatment. Interventions for storage LUTS are available, but must be selected judiciously, using particular caution if nocturia is prominent. In order to achieve better outcomes, a rational stepwise approach to decision making is needed.

摘要

男性下尿路症状(LUTS)很常见,会引起明显的不适并降低生活质量。LUTS 是一系列症状,可能是也可能不是由于良性前列腺增生(BPO)引起的。LUTS 分为储尿期、排尿期或排尿后症状,需要根据其影响、机制和治疗选择来考虑。在大多数患者中,存在多种症状的混合。为了更好地了解哪些症状会影响生活质量,应进行全面评估,包括病史、检查、经过验证的症状问卷、膀胱日记和尿流率(结合剩余尿量测量)。其他测试,特别是尿动力学测试,可能有助于指导治疗选择,特别是对于手术。男性 LUTS 的管理根据潜在机制进行定制。根据患者的个体偏好,有不同的治疗方法可供选择。这些方法包括观察等待、行为和饮食改变、以及/或药物治疗(单独使用或联合使用)。对于有明显排尿困难的严重 BPO 患者,可能需要手术缓解 BPO,并且愿意接受与不可逆治疗相关的风险。对于储尿期症状,有可用的干预措施,但必须谨慎选择,如果夜尿症突出,则更需特别注意。为了获得更好的结果,需要采用合理的分步决策方法。

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